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anti-ABCB7 antibody :: Rabbit ABCB7 Polyclonal Antibody

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Catalog # MBS9134691
Unit / Price
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  0.05 mL  /  $230 +1 FREE 8GB USB
  0.1 mL  /  $305 +1 FREE 8GB USB
  0.2 mL  /  $460 +1 FREE 8GB USB
Product Name

ABCB7, Polyclonal Antibody

Full Product Name

ABCB7 Polyclonal Antibody

Product Synonym Names
ABC7; ASAT; Atm1p; EST140535
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence
AIVGGSGSGK STIVRLLFRF YEPQKGSIYL AGQNIQDVSL ESLRRAVGVV PQDAVLFHNT IYYNLLYGNI SASPEEVYAV AKLAGLHDAI LRMPHGYDTQ VGERGLKLSG GEKQRVAIAR AILKDPPVIL YDEATSSLDS ITEETILGAM KDVVKHRTSI FIAHRLSTVV DADEIIVLDQ GKVAERGTHH GLLANPHSIY SEMWHTQSSR VQNHDNPKWE AKKENISKEE ERKKLQEEIV NSVKGCGNCS C
OMIM
AB005289 mRNA
3D Structure
ModBase 3D Structure for O75027
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Purity/Purification
Affinity Purification
Immunogen
Recombinant protein of human ABCB7
Immunogen Species
Human
Storage Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Cellular Location
Mitochondrion inner membrane, Multi-pass membrane protein
Preparation and Storage
Store at -20 degree C. Avoid freeze / thaw cycles.
Other Notes
Small volumes of anti-ABCB7 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-ABCB7 antibody
The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. This gene encodes a half-transporter involved in the transport of heme from the mitochondria to the cytosol. With iron/sulfur cluster precursors as its substrates, this protein may play a role in metal homeostasis. Mutations in this gene have been associated with mitochondrial iron accumulation and isodicentric (X)(q13) and sideroblastic anemia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Product Categories/Family for anti-ABCB7 antibody
Applications Tested/Suitable for anti-ABCB7 antibody
Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
Application Notes for anti-ABCB7 antibody
WB: 1:500 - 1:2000
IHC: 1:50 - 1:200
IF: 1:50 - 1:200

Western Blot (WB) of anti-ABCB7 antibody
Western blot analysis of extracts of various cell lines, using ABCB7 antibody at 1:1000 dilution.
Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (MBS128200) at 1:10000 dilution.
Lysates/proteins: 25ug per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit.
Exposure time: 10s.
anti-ABCB7 antibody Western Blot (WB) (WB) image
Immunohistochemistry (IHC) of anti-ABCB7 antibody
Immunohistochemistry of paraffin-embedded human liver using ABCB7 antibody at dilution of 1:100 (40x lens).
anti-ABCB7 antibody Immunohistochemistry (IHC) (IHC) image
Immunohistochemistry (IHC) of anti-ABCB7 antibody
Immunohistochemistry of paraffin-embedded human gastric cancer using ABCB7 antibody at dilution of 1:100 (40x lens).
anti-ABCB7 antibody Immunohistochemistry (IHC) (IHC) image
Immunohistochemistry (IHC) of anti-ABCB7 antibody
Immunohistochemistry of paraffin-embedded rat heart using ABCB7 antibody at dilution of 1:100 (40x lens).
anti-ABCB7 antibody Immunohistochemistry (IHC) (IHC) image
Immunohistochemistry (IHC) of anti-ABCB7 antibody
Immunohistochemistry of paraffin-embedded mouse heart using ABCB7 antibody at dilution of 1:100 (40x lens).
anti-ABCB7 antibody Immunohistochemistry (IHC) (IHC) image
Immunohistochemistry (IHC) of anti-ABCB7 antibody
Immunohistochemistry of paraffin-embedded mouse lung using ABCB7 antibody at dilution of 1:100 (40x lens).
anti-ABCB7 antibody Immunohistochemistry (IHC) (IHC) image
NCBI/Uniprot data below describe general gene information for ABCB7. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
Calculated: 78kDa; 82kDa
Observed: 83kDa
NCBI Official Full Name
ATP-binding cassette sub-family B member 7, mitochondrial isoform 2
NCBI Official Synonym Full Names
ATP binding cassette subfamily B member 7
NCBI Official Symbol
ABCB7  [Similar Products]
NCBI Official Synonym Symbols
ABC7; ASAT; Atm1p; EST140535
  [Similar Products]
NCBI Protein Information
ATP-binding cassette sub-family B member 7, mitochondrial
UniProt Protein Name
ATP-binding cassette sub-family B member 7, mitochondrial
UniProt Synonym Protein Names
ATP-binding cassette transporter 7; ABC transporter 7 protein
Protein Family
UniProt Gene Name
ABCB7  [Similar Products]
UniProt Synonym Gene Names
ABC7; ABC transporter 7 protein  [Similar Products]
NCBI Summary for ABCB7
The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. This gene encodes a half-transporter involved in the transport of heme from the mitochondria to the cytosol. With iron/sulfur cluster precursors as its substrates, this protein may play a role in metal homeostasis. Mutations in this gene have been associated with mitochondrial iron accumulation and isodicentric (X)(q13) and sideroblastic anemia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2012]
UniProt Comments for ABCB7
Could be involved in the transport of heme from the mitochondria to the cytosol. Plays a central role in the maturation of cytosolic iron-sulfur (Fe/S) cluster-containing proteins.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Products associated with anti-ABCB7 antibody
 Reference Product  PubMed Publications
 FECH antibody  >1 publications with ABCB7 and FECH
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