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anti-ABCD1 antibody :: Rabbit ABCD1 Polyclonal Antibody

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Catalog # MBS8213868
Unit / Price
  0.03 mL  /  $155 +1 FREE 8GB USB
  0.1 mL  /  $220 +1 FREE 8GB USB
  0.2 mL  /  $295 +1 FREE 8GB USB
Western Blot (WB)
Product Name

ABCD1, Polyclonal Antibody

Also Known As

Anti-ABCD1 Antibody

Product Synonym Names
ALD; ATP-binding cassette sub-family D member 1; Adrenoleukodystrophy protein; ALDP
Antibody/Peptide Pairs
ABCD1 peptide (MBS8238055) is used for blocking the activity of ABCD1 antibody (MBS8213868)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence Length
3D Structure
ModBase 3D Structure for P33897
Species Reactivity
Human, Mouse, Rat
Recognizes endogenous levels of ABCD1 protein.
The antibody was purified by immunogen affinity chromatography.
Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
KLH-conjugated synthetic peptide encompassing a sequence within the center region of human ABCD1. The exact sequence is proprietary.
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C for one year. Avoid freeze/thaw cycles.
Other Notes
Small volumes of anti-ABCD1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-ABCD1 antibody
Rabbit polyclonal antibody to ABCD1
Applications Tested/Suitable for anti-ABCD1 antibody
Western Blot (WB)
Application Notes for anti-ABCD1 antibody
WB (1/500 - 1/1000)

Western Blot (WB) of anti-ABCD1 antibody
Western blot analysis of ABCD1 expression in HeLa (A), mouse brain (B), rat kidney (C) whole cell lysates.
anti-ABCD1 antibody Western Blot (WB) (WB) image
NCBI/Uniprot data below describe general gene information for ABCD1. It may not necessarily be applicable to this product.
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
82,937 Da
NCBI Official Full Name
ATP-binding cassette sub-family D member 1
NCBI Official Synonym Full Names
ATP-binding cassette, sub-family D (ALD), member 1
NCBI Official Symbol
ABCD1  [Similar Products]
NCBI Official Synonym Symbols
  [Similar Products]
NCBI Protein Information
ATP-binding cassette sub-family D member 1
UniProt Protein Name
ATP-binding cassette sub-family D member 1
UniProt Synonym Protein Names
Adrenoleukodystrophy protein; ALDP
Protein Family
UniProt Gene Name
ABCD1  [Similar Products]
UniProt Synonym Gene Names
ALD; ALDP  [Similar Products]
UniProt Entry Name
NCBI Summary for ABCD1
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ALD subfamily, which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. All known peroxisomal ABC transporters are half transporters which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. This peroxisomal membrane protein is likely involved in the peroxisomal transport or catabolism of very long chain fatty acids. Defects in this gene have been identified as the underlying cause of adrenoleukodystrophy, an X-chromosome recessively inherited demyelinating disorder of the nervous system. [provided by RefSeq, Jul 2008]
UniProt Comments for ABCD1
ABCD1: Probable transporter. The nucleotide-binding fold acts as an ATP-binding subunit with ATPase activity. Defects in ABCD1 are the cause of adrenoleukodystrophy X- linked (X-ALD). X-ALD is a peroxisomal metabolic disorder characterized by progressive multifocal demyelination of the central nervous system and by peripheral adrenal insufficiency (Addison disease). It results in mental deterioration, corticospinal tract dysfunction, and cortical blindness. Different clinical manifestations exist like: cerebral childhood ALD (CALD), adult cerebral ALD (ACALD), adrenomyeloneuropathy (AMN) and 'Addison disease only' (ADO) phenotype. The promoter region of ABCD1 is deleted in the chromosome Xq28 deletion syndrome which involves ABCD1 and the neighboring gene BCAP31. Belongs to the ABC transporter superfamily. ABCD family. Peroxisomal fatty acyl CoA transporter (TC 3.A.1.203) subfamily.

Protein type: Transporter; Hydrolase; Membrane protein, multi-pass; Transporter, ABC family; Membrane protein, integral; Mitochondrial

Chromosomal Location of Human Ortholog: Xq28

Cellular Component: peroxisomal membrane; integral to peroxisomal membrane; membrane; mitochondrion; perinuclear region of cytoplasm; cytoplasm; peroxisome; cytosol

Molecular Function: identical protein binding; protein binding; enzyme binding; protein homodimerization activity; peroxisomal fatty acyl CoA transporter activity; ATPase activity, coupled to transmembrane movement of substances; transporter activity; ATPase activity; ATP binding

Biological Process: fatty acid beta-oxidation using acyl-CoA oxidase; peroxisomal membrane transport; fatty acid beta-oxidation; peroxisomal long-chain fatty acid import; very-long-chain fatty acid catabolic process; peroxisome organization and biogenesis; unsaturated fatty acid metabolic process; linoleic acid metabolic process; cellular lipid metabolic process; transmembrane transport; long-chain fatty acid catabolic process

Disease: Adrenoleukodystrophy
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