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anti-ABCD4 antibody :: Rabbit ABCD4 Polyclonal Antibody

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Catalog # MBS821070
Unit / Price
  0.03 mL  /  $155 +1 FREE 8GB USB
  0.1 mL  /  $220 +1 FREE 8GB USB
  0.2 mL  /  $295 +1 FREE 8GB USB
Immunohistochemistry (IHC)
Product Name

ABCD4, Polyclonal Antibody

Also Known As

Anti-ABCD4 Antibody

Product Synonym Names
PXMP1L; ATP-binding cassette sub-family D member 4; PMP70-related protein; P70R; Peroxisomal membrane protein 1-like; PXMP1-L; Peroxisomal membrane protein 69; PMP69
Antibody/Peptide Pairs
ABCD4 peptide (MBS824033) is used for blocking the activity of ABCD4 antibody (MBS821070)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence Length
606
OMIM
gene 614857
3D Structure
ModBase 3D Structure for O14678
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Specificity
Recognizes endogenous levels of ABCD4 protein.
Purity/Purification
The antibody was purified by immunogen affinity chromatography.
Form/Format
Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Immunogen
KLH-conjugated synthetic peptide encompassing a sequence within the center region of human ABCD4. The exact sequence is proprietary.
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C for one year. Avoid freeze/thaw cycles.
Other Notes
Small volumes of anti-ABCD4 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-ABCD4 antibody
Rabbit polyclonal antibody to ABCD4
Applications Tested/Suitable for anti-ABCD4 antibody
Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-ABCD4 antibody
WB (1/500 - 1/1000), IH (1/100 - 1/200)

Western Blot (WB) of anti-ABCD4 antibody
anti-ABCD4 antibody Western Blot (WB) (WB) image
Immunohistochemistry (IHC) of anti-ABCD4 antibody
Immunohistochemical analysis of ABCD4 staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX.
anti-ABCD4 antibody Immunohistochemistry (IHC) (IHC) image
NCBI/Uniprot data below describe general gene information for ABCD4. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
68,597 Da
NCBI Official Full Name
ATP-binding cassette sub-family D member 4
NCBI Official Synonym Full Names
ATP-binding cassette, sub-family D (ALD), member 4
NCBI Official Symbol
ABCD4  [Similar Products]
NCBI Official Synonym Symbols
P70R; P79R; ABC41; MAHCJ; PMP69; PXMP1L; EST352188
  [Similar Products]
NCBI Protein Information
ATP-binding cassette sub-family D member 4; PXMP1-L; PMP70-related protein; peroxisomal membrane protein 69; 69 kDa peroxisomal ABC-transporter
UniProt Protein Name
ATP-binding cassette sub-family D member 4
UniProt Synonym Protein Names
PMP70-related protein; P70R; Peroxisomal membrane protein 1-like; PXMP1-L; Peroxisomal membrane protein 69; PMP69
UniProt Gene Name
ABCD4  [Similar Products]
UniProt Synonym Gene Names
PXMP1L; P70R; PXMP1-L; PMP69  [Similar Products]
UniProt Entry Name
ABCD4_HUMAN
NCBI Summary for ABCD4
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ALD subfamily, which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. All known peroxisomal ABC transporters are half transporters which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. The function of this peroxisomal membrane protein is unknown. However, it is speculated that it may function as a heterodimer for another peroxisomal ABC transporter and, therefore, may modify the adrenoleukodystrophy phenotype. It may also play a role in the process of peroxisome biogenesis. Alternative splicing results in at least two different transcript variants, one which is protein-coding and one which is probably not protein-coding. [provided by RefSeq, Jul 2008]
UniProt Comments for ABCD4
ABCD4: is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ALD subfamily, which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. All known peroxisomal ABC transporters are half transporters which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. The function of this peroxisomal membrane protein is unknown. However, it is speculated that it may function as a heterodimer for another peroxisomal ABC transporter and, therefore, may modify the adrenoleukodystrophy phenotype. It may also play a role in the process of peroxisome biogenesis. Alternative splicing results in at least two different transcript variants, one which is protein-coding and one which is probably not protein-coding. [provided by RefSeq, Jul 2008]

Protein type: Transporter; Membrane protein, integral; Transporter, ABC family; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 14q24.3

Cellular Component: peroxisomal membrane; endoplasmic reticulum membrane; lysosomal membrane; integral to membrane; peroxisome; ATP-binding cassette (ABC) transporter complex

Molecular Function: ATPase activity, coupled to transmembrane movement of substances; ATP binding

Biological Process: vitamin metabolic process; cobalamin metabolic process; transmembrane transport; water-soluble vitamin metabolic process

Disease: Methylmalonic Aciduria And Homocystinuria, Cblj Type
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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