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anti-ACTG1 antibody :: Rabbit ACTG1 Polyclonal Antibody

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Catalog # MBS9401579
Unit / Price
  0.05 mL  /  $200 +1 FREE 8GB USB
  0.1 mL  /  $255 +1 FREE 8GB USB
Testing Data
Product Name

ACTG1, Polyclonal Antibody

Also Known As

ACTG1 Antibody

Product Synonym Names
actin, gamma 1, ACT, ACTG, BRWS2, DFNA20, DFNA26
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence Length
1812
OMIM
102560
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Specificity
The antibody detects endogenous level of total ACTG1 protein.
Form/Format
Supplied at 0.7mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.3, 0.05% sodium azide and 50% glycerol.
Immunogen Type
Recombinant Protein
Immunogen Description
Fusion protein corresponding to a region derived from 4-379 amino acids of human actin, gamma 1
Target Name
ACTG1
Preparation and Storage
Store at -20 degree C/1 year
Other Notes
Small volumes of anti-ACTG1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-ACTG1 antibody
Actins are highly conserved proteins that are involved in various types of cell motility, and maintenance of the cytoskeleton. In vertebrates, three main groups of actin isoforms, alpha, beta and gamma have been identified. The alpha actins are found in muscle tissues and are a major constituent of the contractile apparatus. The beta and gamma actins co-exist in most cell types as components of the cytoskeleton, and as mediators of internal cell motility. Actin, gamma 1, encoded by this gene, is a cytoplasmic actin found in non-muscle cells. Mutations in this gene are associated with DFNA20/26, a subtype of autosomal dominant non-syndromic sensorineural progressive hearing loss. Alternative splicing results in multiple transcript variants.
Product Categories/Family for anti-ACTG1 antibody
Applications Tested/Suitable for anti-ACTG1 antibody
ELISA (EIA), Western Blot (WB)
Application Notes for anti-ACTG1 antibody
ELISA: 1:2000-1:5000
Western blotting: 1:500-1:2000

Testing Data of anti-ACTG1 antibody
Gel: 10%+12%SDS-PAGE Lysate: 40 ug Human lymphoma tissue lysate Primary antibody: 1/350 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 1 second
anti-ACTG1 antibody Testing Data image
NCBI/Uniprot data below describe general gene information for ACTG1. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
41,793 Da
NCBI Official Full Name
Homo sapiens actin, gamma 1, mRNA
NCBI Official Synonym Full Names
actin gamma 1
NCBI Official Symbol
ACTG1  [Similar Products]
NCBI Official Synonym Symbols
ACT; ACTG; BRWS2; DFNA20; DFNA26; HEL-176
  [Similar Products]
NCBI Protein Information
actin, cytoplasmic 2
UniProt Protein Name
Actin, cytoplasmic 2
UniProt Synonym Protein Names
Gamma-actin
Protein Family
UniProt Gene Name
ACTG1  [Similar Products]
UniProt Synonym Gene Names
UniProt Entry Name
ACTG_HUMAN
NCBI Summary for ACTG1
Actins are highly conserved proteins that are involved in various types of cell motility, and maintenance of the cytoskeleton. In vertebrates, three main groups of actin isoforms, alpha, beta and gamma have been identified. The alpha actins are found in muscle tissues and are a major constituent of the contractile apparatus. The beta and gamma actins co-exist in most cell types as components of the cytoskeleton, and as mediators of internal cell motility. Actin, gamma 1, encoded by this gene, is a cytoplasmic actin found in non-muscle cells. Mutations in this gene are associated with DFNA20/26, a subtype of autosomal dominant non-syndromic sensorineural progressive hearing loss. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Jan 2011]
UniProt Comments for ACTG1
ACTG1: Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. Polymerization of globular actin (G-actin) leads to a structural filament (F-actin) in the form of a two-stranded helix. Each actin can bind to 4 others. Belongs to the actin family.

Protein type: Motility/polarity/chemotaxis; Cytoskeletal

Chromosomal Location of Human Ortholog: 17q25

Cellular Component: filamentous actin; extracellular space; cytoskeleton; membrane; myofibril; plasma membrane; cytosol; nucleus

Molecular Function: identical protein binding; protein binding; structural constituent of cytoskeleton; ubiquitin protein ligase binding; ATP binding

Biological Process: axon guidance; retinal homeostasis; intercellular junction assembly and maintenance; ephrin receptor signaling pathway; innate immune response; sarcomere organization; cell motility; vascular endothelial growth factor receptor signaling pathway

Disease: Baraitser-winter Syndrome 2; Deafness, Autosomal Dominant 20
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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