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anti-ADAMTS18 antibody :: Rabbit ADAMTS18 Polyclonal Antibody

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Catalog # MBS854348
Unit / Price
  0.1 mg  /  $330 +1 FREE 8GB USB
Product Name

ADAMTS18, Polyclonal Antibody

Full Product Name

ADAMTS18 Antibody

Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
OMIM
607512
3D Structure
ModBase 3D Structure for Q8TE60
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human
Predicted: Mouse, Rat
Form/Format
Purified by protein A column containing 0.02% NaN3
Preparation and Storage
Already reconstituted in 200ul sterile H2O. The antibody is stable for at least one year when stored at-20 degree C after reconstitution. Avoid repeated freeze/defrost cycles.
Other Notes
Small volumes of anti-ADAMTS18 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-ADAMTS18 antibody
Rabbit polyclonal ADAMTS18(1) antibody was raised against a recombinate human ADAMTS18 protein 712-970aa (BC063283).
Applications Tested/Suitable for anti-ADAMTS18 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-ADAMTS18 antibody
ELISA: 1:20,000-1:80,000
WB: 1:500-1:1,000
IHC: 1:100-1:500

Testing Data of anti-ADAMTS18 antibody
anti-ADAMTS18 antibody Testing Data image
Testing Data of anti-ADAMTS18 antibody
anti-ADAMTS18 antibody Testing Data image
NCBI/Uniprot data below describe general gene information for ADAMTS18. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
119,768 Da
NCBI Official Full Name
A disintegrin and metalloproteinase with thrombospondin motifs 18 isoform 1 preproprotein
NCBI Official Synonym Full Names
ADAM metallopeptidase with thrombospondin type 1 motif 18
NCBI Official Symbol
ADAMTS18  [Similar Products]
NCBI Official Synonym Symbols
KNO2; MMCAT; ADAMTS21
  [Similar Products]
NCBI Protein Information
A disintegrin and metalloproteinase with thrombospondin motifs 18
UniProt Protein Name
A disintegrin and metalloproteinase with thrombospondin motifs 18
UniProt Gene Name
ADAMTS18  [Similar Products]
UniProt Synonym Gene Names
ADAMTS21; ADAM-TS 18; ADAM-TS18; ADAMTS-18  [Similar Products]
NCBI Summary for ADAMTS18
This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. ADAMTS family members share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The encoded preproprotein is proteolytically processed to generate the mature protein, which may regulate hemostatic balance and function as a tumor suppressor. Mutations in this gene may be associated with microcornea, myopic chorioretinal atrophy, and telecanthus (MMCAT) and cone-rod dystrophy in human patients. [provided by RefSeq, May 2016]
UniProt Comments for ADAMTS18
CautionVariant Leu-179 has been originally reported as disease-causing mutation in a patient with Knobloch syndrome (PubMed:21862674). It has been subsequently shown that Knobloch syndrome in the patient was due to an intronic mutation in COL18A1. Variant Leu-179 is, therefore, not responsible for the disease phenotype (PubMed:23667181).
Product References and Citations for anti-ADAMTS18 antibody
(1) Wei, X., Prickett, T.D., Viloria, C.G., et al. Mutational and functional analysis reveals ADAMTS18 metalloproteinase as a novel driver in melanoma. Mol. Cancer Res. 8 (11), 1513-1525 (2010).

Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

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