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anti-ADAMTSL5 antibody :: Chicken ADAMTSL5 Polyclonal Antibody

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Catalog # MBS150785
Unit / Price
  0.1 mg  /  $375 +1 FREE 8GB USB
Product Name

ADAMTSL5, Polyclonal Antibody

Also Known As

ADAMTSL5 Antibody

Product Synonym Names
ADAMTSL5; THSD6; THSD6; ADAMTS-like protein 5; Thrombospondin type-1 domain-containing protein 6; ADAMTSL-5; ADAMTS-like 5
Antibody/Peptide Pairs
ADAMTSL5 peptide (MBS151994) is used for blocking the activity of ADAMTSL5 antibody (MBS150785)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence Length
471
3D Structure
ModBase 3D Structure for Q6ZMM2
Clonality
Polyclonal
Isotype
IgY
Host
Chicken
Species Reactivity
Human, Mouse, Rat
Purity/Purification
ADAMTSL5 Antibody is affinity chromatography purified via peptide column.
Form/Format
Liquid
Concentration
1 mg/mL (lot specific)
Conjugate
Unconjugated
Immunogen
ADAMTSL5 antibody was raised against a 17 amino acid synthetic peptide near the carboxy terminus of human ADAMTSL5.
Buffer
ADAMTSL5 Antibody is supplied in PBS containing 0.02% sodium azide.
Preparation and Storage
ADAMTSL5 antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Other Notes
Small volumes of anti-ADAMTSL5 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-ADAMTSL5 antibody
ADAMTSL5 Antibody: ADAMTSL5 belongs to a large superfamily containing 20 ADAMTS proteases and at least eight ADAMTS-like proteins. ADAMTS proteases are secreted enzymes with a conserved organization that includes a metalloprotease domain and an ancillary domain containing one or more thrombospondin type 1 repeats (TSR). The ADAMTS-like subfamily comprises proteins homologous to the ADAMTS ancillary domains but lacking the protease domain and hence lacking catalytic activity. The exact role of ADAMTSL5 is currently unknown, but other ADAMTS-like proteins appear to have regulatory roles in the extracellular matrix.
Applications Tested/Suitable for anti-ADAMTSL5 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
Application Notes for anti-ADAMTSL5 antibody
ADAMTSL5 antibody can be used for detection of ADAMTSL5 by Western blot at 1 mug/mL. Antibody can also be used for immunohistochemistry starting at 5 mug/mL. For immunofluorescence start at 20 mug/mL.

Western Blot (WB) of anti-ADAMTSL5 antibody
Western blot analysis of ADAMTSL5 in human skeletal muscle tissue lysate with ADAMTSL5 antibody at 1 μg/mL.
anti-ADAMTSL5 antibody Western Blot (WB) (WB) image
Immunofluorescence (IF) of anti-ADAMTSL5 antibody
Immunofluorescence of ADAMTSL5 in mouse skeletal muscle tissue with ADAMTSL5 antibody at 20 μg/mL.
anti-ADAMTSL5 antibody Immunofluorescence (IF) image
Immunohistochemistry (IHC) of anti-ADAMTSL5 antibody
Immunohistochemistry of ADAMTSL5 in mouse skeletal muscle tissue with ADAMTSL5 antibody at 5 μg/mL.
anti-ADAMTSL5 antibody Immunohistochemistry (IHC) (IHC) image
NCBI/Uniprot data below describe general gene information for ADAMTSL5. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
53,171 Da
NCBI Official Full Name
ADAMTS-like protein 5
NCBI Official Synonym Full Names
ADAMTS-like 5
NCBI Official Symbol
ADAMTSL5  [Similar Products]
NCBI Official Synonym Symbols
THSD6
  [Similar Products]
NCBI Protein Information
ADAMTS-like protein 5; ADAMTSL-5; thrombospondin, type I, domain containing 6; thrombospondin type-1 domain-containing protein 6
UniProt Protein Name
ADAMTS-like protein 5
UniProt Synonym Protein Names
Thrombospondin type-1 domain-containing protein 6
Protein Family
UniProt Gene Name
ADAMTSL5  [Similar Products]
UniProt Synonym Gene Names
THSD6; ADAMTSL-5  [Similar Products]
UniProt Entry Name
ATL5_HUMAN
UniProt Comments for ADAMTSL5
ADAMTSL5: May play a role in modulation of fibrillin microfibrils in the extracellular matrix (ECM). Interacts with heparin, FBN1 and FBN2. 2 isoforms of the human protein are produced by alternative splicing

Protein type: Secreted; Secreted, signal peptide; Protease; Extracellular matrix

Chromosomal Location of Human Ortholog: 19p13.3

Cellular Component: proteinaceous extracellular matrix; microfibril; extracellular region

Molecular Function: heparin binding; zinc ion binding; metalloendopeptidase activity

Biological Process: proteolysis
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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