NP_001110.2
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
alpha-adducin isoform a
NCBI Official Synonym Full Names
adducin 1 (alpha)
NCBI Official Synonym Symbols
NCBI Protein Information
alpha-adducin
UniProt Protein Name
Alpha-adducin
UniProt Synonym Protein Names
Erythrocyte adducin subunit alpha
UniProt Synonym Gene Names
UniProt Entry Name
ADDA_HUMAN
NCBI Summary for ADD1
Adducins are a family of cytoskeleton proteins encoded by three genes (alpha, beta, gamma). Adducin is a heterodimeric protein that consists of related subunits, which are produced from distinct genes but share a similar structure. Alpha- and beta-adducin include a protease-resistant N-terminal region and a protease-sensitive, hydrophilic C-terminal region. Alpha- and gamma-adducins are ubiquitously expressed. In contrast, beta-adducin is expressed at high levels in brain and hematopoietic tissues. Adducin binds with high affinity to Ca(2+)/calmodulin and is a substrate for protein kinases A and C. Alternative splicing results in multiple variants encoding distinct isoforms; however, not all variants have been fully described. [provided by RefSeq, Jul 2008]
UniProt Comments for ADD1
Membrane-cytoskeleton-associated protein that promotes the assembly of the spectrin-actin network. Binds to calmodulin.
Research Articles on ADD1
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Products associated with anti-ADD1 antibody
Pathways associated with anti-ADD1 antibody
Diseases associated with anti-ADD1 antibody
Organs/Tissues associated with anti-ADD1 antibody
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