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anti-ADRBK2 antibody :: Rabbit adrenergic, beta, receptor kinase 2 Polyclonal Antibody

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Catalog # MBS713681
Unit / Price
  0.05 mL  /  $230 +1 FREE 8GB USB
  0.15 mL  /  $500 +1 FREE 8GB USB
anti-ADRBK2 antibody
Product Name

adrenergic, beta, receptor kinase 2 (ADRBK2), Polyclonal Antibody

Also Known As

Rabbit anti-human adrenergic, beta, receptor kinase 2 polyclonal Antibody

Product Synonym Names
adrenergic; beta; receptor kinase 2; ADRBK2; BARK2; GRK3
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence Length
688
OMIM
109636
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Purity/Purification
Antigen Affinity Purified
Immunogen
Human ADRBK2
Storage Buffer
PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20 degree C, Avoid freeze / thaw cycles.
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-28891 / sc-563
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of anti-ADRBK2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for anti-ADRBK2 antibody
ELISA (EIA), Western Blot (WB)
NCBI/Uniprot data below describe general gene information for ADRBK2. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
79,710 Da[Similar Products]
NCBI Official Full Name
adrenergic, beta, receptor kinase 2, isoform CRA_b
NCBI Official Synonym Full Names
adrenergic, beta, receptor kinase 2
NCBI Official Symbol
ADRBK2  [Similar Products]
NCBI Official Synonym Symbols
GRK3; BARK2
  [Similar Products]
NCBI Protein Information
beta-adrenergic receptor kinase 2; beta-ARK-2; G-protein-coupled receptor kinase 3
UniProt Protein Name
Beta-adrenergic receptor kinase 2
UniProt Synonym Protein Names
G-protein-coupled receptor kinase 3
UniProt Gene Name
ADRBK2  [Similar Products]
UniProt Synonym Gene Names
BARK2; GRK3; Beta-ARK-2  [Similar Products]
UniProt Entry Name
ARBK2_HUMAN
NCBI Summary for ADRBK2
The beta-adrenergic receptor kinase specifically phosphorylates the agonist-occupied form of the beta-adrenergic and related G protein-coupled receptors. Overall, the beta adrenergic receptor kinase 2 has 85% amino acid similarity with beta adrenergic receptor kinase 1, with the protein kinase catalytic domain having 95% similarity. These data suggest the existence of a family of receptor kinases which may serve broadly to regulate receptor function. [provided by RefSeq, Jul 2008]
UniProt Comments for ADRBK2
GRK3: Specifically phosphorylates the agonist-occupied form of the beta-adrenergic and closely related receptors. Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.

Protein type: Protein kinase, AGC; EC 2.7.11.15; Protein kinase, Ser/Thr (non-receptor); Kinase, protein; AGC group; GRK family; BARK subfamily

Chromosomal Location of Human Ortholog: 22q12.1

Molecular Function: G-protein coupled receptor kinase activity; beta-adrenergic receptor kinase activity; ATP binding; protein kinase activity

Biological Process: receptor internalization; signal transduction; protein amino acid phosphorylation
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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