NP_064695.3
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
36,020 Da
NCBI Official Full Name
aldo-keto reductase family 1 member B10
NCBI Official Synonym Full Names
aldo-keto reductase family 1, member B10 (aldose reductase)
NCBI Official Synonym Symbols
HIS; HSI; ARL1; ARL-1; ALDRLn; AKR1B11; AKR1B12 [Similar Products]
NCBI Protein Information
aldo-keto reductase family 1 member B10; ARP; hARP; SI reductase; aldose reductase-like 1; small intestine reductase; aldose reductase-like peptide; aldose reductase-related protein; aldo-keto reductase family 1, member B11 (aldose reductase-like)
UniProt Protein Name
Aldo-keto reductase family 1 member B10
UniProt Synonym Protein Names
ARL-1; Aldose reductase-like; Aldose reductase-related protein; ARP; hARP; Small intestine reductase; SI reductase
UniProt Synonym Gene Names
UniProt Entry Name
AK1BA_HUMAN
NCBI Summary for AKR1B10
This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. This member can efficiently reduce aliphatic and aromatic aldehydes, and it is less active on hexoses. It is highly expressed in adrenal gland, small intestine, and colon, and may play an important role in liver carcinogenesis. [provided by RefSeq, Jul 2008]
UniProt Comments for AKR1B10
AKR1B10: Acts as all-trans-retinaldehyde reductase. Can efficiently reduce aliphatic and aromatic aldehydes, and is less active on hexoses (in vitro). May be responsible for detoxification of reactive aldehydes in the digested food before the nutrients are passed on to other organs. Belongs to the aldo/keto reductase family.
Protein type: EC 1.1.1.21; Carbohydrate Metabolism - butanoate; Lipid Metabolism - linoleic acid; Carbohydrate Metabolism - fructose and mannose; EC 1.1.1.-; Oxidoreductase
Chromosomal Location of Human Ortholog: 7q33
Cellular Component: lysosome; cytosol
Molecular Function: protein binding; aldo-keto reductase activity; indanol dehydrogenase activity; geranylgeranyl reductase activity; retinal dehydrogenase activity
Biological Process: steroid metabolic process; phototransduction, visible light; digestion; aldehyde metabolic process; farnesol catabolic process; retinoid metabolic process
Research Articles on AKR1B10
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Products associated with anti-AKR1B10 antibody
Pathways associated with anti-AKR1B10 antibody
Diseases associated with anti-AKR1B10 antibody
Organs/Tissues associated with anti-AKR1B10 antibody
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