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anti-ALDH3A2 antibody :: Rabbit aldehyde dehydrogenase 3 family, member A2 Polyclonal Antibody

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Catalog # MBS712656
Unit / Price
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  0.05 mL  /  $230 +1 FREE 8GB USB
  0.15 mL  /  $500 +1 FREE 8GB USB
anti-ALDH3A2 antibody
Product Name

aldehyde dehydrogenase 3 family, member A2 (ALDH3A2), Polyclonal Antibody

Full Product Name

Rabbit anti-human aldehyde dehydrogenase 3 family, member A2 polyclonal Antibody

Product Synonym Names
aldehyde dehydrogenase 3 family; member A2; ALDH3A2; ALDH10; DKFZp686E23276; FALDH; FLJ20851; SLS
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
OMIM
609523
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Purity/Purification
Antigen Affinity Purified
Immunogen
Human ALDH3A2
Storage Buffer
PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20 degree C, Avoid freeze / thaw cycles.
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-74315 / sc-74320 / sc-68892
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of anti-ALDH3A2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for anti-ALDH3A2 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
NCBI/Uniprot data below describe general gene information for ALDH3A2. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
57,669 Da[Similar Products]
NCBI Official Full Name
Aldehyde dehydrogenase 3 family, member A2
NCBI Official Synonym Full Names
aldehyde dehydrogenase 3 family, member A2
NCBI Official Symbol
ALDH3A2  [Similar Products]
NCBI Official Synonym Symbols
SLS; FALDH; ALDH10
  [Similar Products]
NCBI Protein Information
fatty aldehyde dehydrogenase; aldehyde dehydrogenase 10; microsomal aldehyde dehydrogenase; aldehyde dehydrogenase family 3 member A2
UniProt Protein Name
Fatty aldehyde dehydrogenase
UniProt Synonym Protein Names
Aldehyde dehydrogenase 10; Aldehyde dehydrogenase family 3 member A2; Microsomal aldehyde dehydrogenase
UniProt Gene Name
ALDH3A2  [Similar Products]
UniProt Synonym Gene Names
ALDH10; FALDH  [Similar Products]
UniProt Entry Name
AL3A2_HUMAN
NCBI Summary for ALDH3A2
Aldehyde dehydrogenase isozymes are thought to play a major role in the detoxification of aldehydes generated by alcohol metabolism and lipid peroxidation. This gene product catalyzes the oxidation of long-chain aliphatic aldehydes to fatty acid. Mutations in the gene cause Sjogren-Larsson syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
UniProt Comments for ALDH3A2
ALDH3A2: Catalyzes the oxidation of long-chain aliphatic aldehydes to fatty acids. Active on a variety of saturated and unsaturated aliphatic aldehydes between 6 and 24 carbons in length. Responsible for conversion of the sphingosine 1-phosphate (S1P) degradation product hexadecenal to hexadecenoic acid. Defects in ALDH3A2 are the cause of Sjoegren-Larsson syndrome (SLS). SLS is an autosomal recessive neurocutaneous disorder characterized by a combination of severe mental retardation, spastic di- or tetraplegia and congenital ichthyosis (increased keratinization). Ichthyosis is usually evident at birth, neurologic symptoms appear in the first or second year of life. Most patients have an IQ of less than 60. Additional clinical features include glistening white spots on the retina, seizures, short stature and speech defects. Belongs to the aldehyde dehydrogenase family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Amino Acid Metabolism - valine, leucine and isoleucine degradation; Membrane protein, integral; EC 1.2.1.3; Amino Acid Metabolism - tryptophan; Mitochondrial; Carbohydrate Metabolism - propanoate; Lipid Metabolism - fatty acid; Amino Acid Metabolism - arginine and proline; Other Amino Acids Metabolism - beta-alanine; Oxidoreductase; Lipid Metabolism - glycerolipid; Carbohydrate Metabolism - butanoate; Carbohydrate Metabolism - glycolysis and gluconeogenesis; Carbohydrate Metabolism - ascorbate and aldarate; Amino Acid Metabolism - histidine; Secondary Metabolites Metabolism - limonene and pinene degradation; Carbohydrate Metabolism - pyruvate; Amino Acid Metabolism - lysine degradation

Chromosomal Location of Human Ortholog: 17p11.2

Cellular Component: endoplasmic reticulum membrane; intracellular membrane-bound organelle; mitochondrial inner membrane; integral to membrane; peroxisome

Molecular Function: long-chain-alcohol oxidase activity; aldehyde dehydrogenase (NAD) activity; aldehyde dehydrogenase [NAD(P)+] activity; 3-chloroallyl aldehyde dehydrogenase activity; long-chain-aldehyde dehydrogenase activity

Biological Process: phytol metabolic process; epidermis development; central nervous system development; aldehyde metabolic process; sesquiterpenoid metabolic process; peripheral nervous system development

Disease: Sjogren-larsson Syndrome
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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