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anti-ALX3 antibody :: Rabbit ALX3 Polyclonal Antibody

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Catalog # MBS834255
Unit / Price
  0.1 mg  /  $390 +1 FREE 8GB USB
Western Blot
Product Name

ALX3, Polyclonal Antibody

Also Known As

ALX3 antibody

Product Synonym Names
Polyclonal ALX3; Anti-ALX3; ALX 3; ALX-3; ALX3
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence Length
343
3D Structure
ModBase 3D Structure for O70137
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Mouse, Rat, Human
Form/Format
Lyophilized powder. Add 100 ul of distilled water. Final antibody concentration is 1 mg/ml in PBS buffer.
Concentration
1 mg/ml (lot specific)
Biological Significance
Mouse Alx3 is a homeobox gene that is related to the Drosophila aristaless gene and to a group of vertebrate genes including Prx1, Prx2, Cart1, and Alx4. The protein encoded contains a diverged variant of a conserved peptide sequence present near the carboxyl terminus of at least 15 different paired-class-homeodomain proteins. Alx3 is expressed in mouse embryos from 8 days of gestation onward in a characteristic pattern, predominantly in neural crest-derived mesenchyme and in lateral plate mesoderm.
Immunogen
ALX3 antibody was raised in rabbit using the N terminal of ALX3 as the immunogen
Preparation and Storage
Store at 4 degree C, following reconstitution, aliquot and store at -20 degree C. Avoid repeated freeze-thaw cycles.
Other Notes
Small volumes of anti-ALX3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-ALX3 antibody
Rabbit polyclonal ALX3 antibody
Product Categories/Family for anti-ALX3 antibody
Applications Tested/Suitable for anti-ALX3 antibody
Western Blot (WB)
Application Notes for anti-ALX3 antibody
WB: 2.5 ug/ml

Western Blot of anti-ALX3 antibody
Western Blot analysis using ALX3 antibody
ALX3 antibody used at 0.2-1 ug/ml to detect target protein.
anti-ALX3 antibody Western Blot (WB) image
NCBI/Uniprot data below describe general gene information for ALX3. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Related Accession #
Molecular Weight
36,851 Da
NCBI Official Full Name
homeobox protein aristaless-like 3
NCBI Official Synonym Full Names
aristaless-like homeobox 3
NCBI Official Symbol
NCBI Protein Information
homeobox protein aristaless-like 3
UniProt Protein Name
Homeobox protein aristaless-like 3
UniProt Synonym Protein Names
Proline-rich transcription factor ALX3
Protein Family
UniProt Gene Name
UniProt Entry Name
ALX3_MOUSE
NCBI Summary for ALX3
This gene belongs to Group 1 of aristaless-like genes, which are characterized by the presence of an aristaless domain and a conserved paired-like homeodomain. The encoded protein acts as a transcriptional regulator. The protein plays a role in the development of craniofacial and appendicular skeleton and may have a role in pancreatic function. [provided by RefSeq, Apr 2013]
UniProt Comments for ALX3
ALX3: Transcriptional regulator with a possible role in patterning of mesoderm during development. Defects in ALX3 are the cause of frontonasal dysplasia type 1 (FND1); also called frontonasal malformation (FNM) or frontorhiny. The term frontonasal dysplasia describes an array of abnormalities affecting the eyes, forehead and nose and linked to midfacial dysraphia. The clinical picture is highly variable. Major findings include true ocular hypertelorism; broadening of the nasal root; median facial cleft affecting the nose and/or upper lip and palate; unilateral or bilateral clefting of the alae nasi; lack of formation of the nasal tip; anterior cranium bifidum occultum; a V-shaped or widow's peak frontal hairline. Belongs to the paired homeobox family.

Protein type: Transcription, coactivator/corepressor; DNA-binding

Cellular Component: nucleus

Molecular Function: DNA binding; sequence-specific DNA binding; transcription factor activity

Biological Process: embryonic forelimb morphogenesis; regulation of apoptosis; transcription, DNA-dependent; regulation of transcription, DNA-dependent; multicellular organismal development; embryonic hindlimb morphogenesis; pattern specification process; embryonic skeletal morphogenesis
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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