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anti-ANKLE1 antibody :: Chicken ANKLE1 Polyclonal Antibody

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Catalog # MBS150337
Unit / Price
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  0.1 mg  /  $375 +1 FREE 8GB USB
Western Blot (WB)
Product Name

ANKLE1, Polyclonal Antibody

Full Product Name

ANKLE1 Antibody

Product Synonym Names
ANKLE1; LEM3; LEMD6; ANKRD41; LEM3; Ankyrin repeat and LEM domain-containing protein 1; Ankyrin repeat domain-containing protein 41; ankyrin repeat and LEM domain containing 1
Antibody/Peptide Pairs
ANKLE1 peptide (MBS152528) is used for blocking the activity of ANKLE1 antibody (MBS150337)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for Q8NAG6
Clonality
Polyclonal
Isotype
IgY
Host
Chicken
Species Reactivity
Human, Mouse, Rat
Specificity
Two isoforms of ANKLE1 are known to exist. ANKLE1 antibody is predicted to not cross-react with ANKLE2
Purity/Purification
ANKLE1 Antibody is affinity chromatography purified via peptide column.
Form/Format
Liquid
Concentration
1 mg/mL (lot specific)
Conjugate
Unconjugated
Immunogen
ANKLE1 antibody was raised against a 15 amino acid synthetic peptide near the carboxy terminus of human ANKLE1.
Buffer
ANKLE1 Antibody is supplied in PBS containing 0.02% sodium azide.
Preparation and Storage
ANKLE1 antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Other Notes
Small volumes of anti-ANKLE1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-ANKLE1 antibody
ANKLE1 Antibody: Ankyrins are membrane adaptor molecules that play important roles in coupling integral membrane proteins to the spectrin-based cytoskeleton network. ANKLE1 (Ankyrin repeat and LEM domain containing 1) is a member of ankyrin repeat and LEM domain containing family. It is a potential single-pass membrane protein that contains ankyrin repeats and a Lem domain. Ankyrin repeats mediate protein-protein interactions and are among the most common structural motifs in known proteins. While the function of this protein is still under investigation, its gene locus has been associated with susceptibility to ovarian and breast cancer.
Applications Tested/Suitable for anti-ANKLE1 antibody
ELISA (EIA), Western Blot (WB)
Application Notes for anti-ANKLE1 antibody
ANKLE1 antibody can be used for detection of ANKLE1 by Western blot at 1 - 2 mug/mL.

Western Blot (WB) of anti-ANKLE1 antibody
Western blot analysis of ANKLE1 in 293 cell lysate with ANKLE1 antibody at (A) 1 and (B) 2 μg/mL.
anti-ANKLE1 antibody Western Blot (WB) (WB) image
NCBI/Uniprot data below describe general gene information for ANKLE1. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
62,255 Da
NCBI Official Full Name
ankyrin repeat and LEM domain-containing protein 1
NCBI Official Synonym Full Names
ankyrin repeat and LEM domain containing 1
NCBI Official Symbol
ANKLE1  [Similar Products]
NCBI Official Synonym Symbols
LEM3; LEMD6; ANKRD41
  [Similar Products]
NCBI Protein Information
ankyrin repeat and LEM domain-containing protein 1; LEM domain containing 6; LEM-domain containing 3; ankyrin repeat domain-containing protein 41
UniProt Protein Name
Ankyrin repeat and LEM domain-containing protein 1
UniProt Synonym Protein Names
Ankyrin repeat domain-containing protein 41; LEM-domain containing protein 3
UniProt Gene Name
ANKLE1  [Similar Products]
UniProt Synonym Gene Names
ANKRD41; LEM3  [Similar Products]
UniProt Entry Name
ANKL1_HUMAN
UniProt Comments for ANKLE1
ANKRD41: 2 isoforms of the human protein are produced by alternative splicing.

Chromosomal Location of Human Ortholog: 19p13.11
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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