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anti-AP3D1 antibody :: Rabbit AP3D1 Polyclonal Antibody

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Catalog # MBS2522537
Unit / Price
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  0.06 mL  /  $195 +1 FREE 8GB USB
  0.12 mL  /  $270 +1 FREE 8GB USB
  0.2 mL  /  $435 +1 FREE 8GB USB
Testing Data
Product Name

AP3D1, Polyclonal Antibody

Popular Item
Full Product Name

AP3D1 Antibody

Product Synonym Names
ADTD; hBLVR
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
OMIM
607246
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Purity/Purification
Antigen affinity purification
Immunogen
Fusion protein of AP3D1
Calculated Molecular Weight
1153aa; 130kd
Observed Molecular Weight
110kd
Buffer
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-49154 / sc-49155 / sc-46772 / sc-46768
Preparation and Storage
Store at -20 degree C. Avoid freeze / thaw cycles
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of anti-AP3D1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-AP3D1 antibody
Adaptor protein (AP) complexes are cytosolic heterotetramers that mediate the sorting of membrane proteins in the secretory and endocytic pathways. AP3D1 is a subunit of the AP-3 complex which is composed of two large adaptins (AP3D1 and AP3B1 or AP3B2), a medium adaptin (AP3M1 or AP3M2) and a small adaptin (APS1 or AP3S2). AP-3 complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes.
Applications Tested/Suitable for anti-AP3D1 antibody
ELISA (EIA), Western Blot (WB)
Application Notes for anti-AP3D1 antibody
WB: 1:200-1:2000

Testing Data of anti-AP3D1 antibody
anti-AP3D1 antibody Testing Data image
NCBI/Uniprot data below describe general gene information for AP3D1. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
AP3D1 protein, partial
NCBI Official Synonym Full Names
adaptor-related protein complex 3, delta 1 subunit
NCBI Official Symbol
AP3D1  [Similar Products]
NCBI Official Synonym Symbols
ADTD; hBLVR
  [Similar Products]
NCBI Protein Information
AP-3 complex subunit delta-1; AP-3 complex delta subunit, partial CDS; adapter-related protein complex 3 subunit delta-1; adaptin, delta; adaptor-related protein complex 3 subunit delta-1; delta adaptin; delta-adaptin, partial CDS; subunit of putative vesicle coat adaptor complex AP-3
UniProt Protein Name
AP-3 complex subunit delta-1
UniProt Synonym Protein Names
AP-3 complex subunit delta; Adaptor-related protein complex 3 subunit delta-1; Delta-adaptin
Protein Family
UniProt Gene Name
AP3D1  [Similar Products]
UniProt Entry Name
AP3D1_HUMAN
NCBI Summary for AP3D1
The protein encoded by this gene is a subunit of the AP3 adaptor-like complex, which is not clathrin-associated, but is associated with the golgi region, as well as more peripheral structures. The AP-3 complex facilitates the budding of vesicles from the golgi membrane, and may be directly involved in trafficking to lysosomes. This subunit is implicated in intracellular biogenesis and trafficking of pigment granules, and possibly platelet dense granules and neurotransmitter vesicles. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011]
UniProt Comments for AP3D1
AP3D1: Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes. Belongs to the adaptor complexes large subunit family. 5 isoforms of the human protein are produced by alternative splicing.

Protein type: Adaptor/scaffold

Chromosomal Location of Human Ortholog: 19p13.3

Cellular Component: Golgi membrane; nucleoplasm; Golgi apparatus; membrane coat; membrane; lysosomal membrane; terminal button; endosome membrane

Molecular Function: transporter activity

Biological Process: intracellular protein transport; protein localization in organelle; melanosome organization and biogenesis; anterograde synaptic vesicle transport; antigen processing and presentation, exogenous lipid antigen via MHC class Ib; synaptic vesicle membrane organization and biogenesis; positive regulation of NK T cell differentiation; anterograde axon cargo transport; eye pigment biosynthetic process
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Pathways associated with anti-AP3D1 antibody
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