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anti-ARF4 antibody :: Rabbit ARF4 Polyclonal Antibody

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Catalog # MBS2519759
Unit / Price
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  0.02 mL  /  $110 +1 FREE 8GB USB
  0.06 mL  /  $150 +1 FREE 8GB USB
  0.12 mL  /  $225 +1 FREE 8GB USB
  0.2 mL  /  $360 +1 FREE 8GB USB
Immunohistochemistry (IHC)
Product Name

ARF4, Polyclonal Antibody

Full Product Name

ARF4 Polyclonal Antibody

Product Synonym Names
ARF2
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
OMIM
601177
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Purity/Purification
Antigen affinity purification
Concentration
0.6mg/mL (lot specific)
Immunogen
Recombinant protein of human ARF4
Buffer
PBS with 0.05% sodium azide, 50% glycerol, pH7.3
Preparation and Storage
Store at -20 degree C (regular) and -80 degree C (long term). Avoid freeze / thaw cycles.
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Other Notes
Small volumes of anti-ARF4 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-ARF4 antibody
This gene is a member of the human ARF gene family whose members encode small guanine nucleotide-binding proteins that stimulate the ADP-ribosyltransferase activity of cholera toxin and play a role in vesicular trafficking and as activators of phospholipase D. The gene products include 5 ARF proteins and 11 ARF-like proteins and constitute one family of the RAS superfamily. The ARF proteins are categorized as class I, class II and class III; this gene is a class II member. The members of each class share a common gene organization. The ARF4 gene spans approximately 12kb and contains six exons and five introns. This gene is the most divergent member of the human ARFs. Conflicting map positions at 3p14 or 3p21 have been reported for this gene.
Applications Tested/Suitable for anti-ARF4 antibody
ELISA (EIA), Immunohistochemistry (IHC)
Application Notes for anti-ARF4 antibody
IHC: 1:15-1:50

Immunohistochemistry (IHC) of anti-ARF4 antibody
Immunohistochemistry of paraffin-embedded Human breast cancer tissue using ARF4 Polyclonal Antibody at dilution 1:20
anti-ARF4 antibody Immunohistochemistry (IHC) (IHC) image
NCBI/Uniprot data below describe general gene information for ARF4. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
20,511 Da
NCBI Official Full Name
ADP-ribosylation factor 4
NCBI Official Synonym Full Names
ADP-ribosylation factor 4
NCBI Official Symbol
NCBI Official Synonym Symbols
NCBI Protein Information
ADP-ribosylation factor 4; ADP-ribosylation factor 2
UniProt Protein Name
ADP-ribosylation factor 4
Protein Family
UniProt Gene Name
UniProt Synonym Gene Names
UniProt Entry Name
ARF4_HUMAN
NCBI Summary for ARF4
This gene is a member of the human ARF gene family whose members encode small guanine nucleotide-binding proteins that stimulate the ADP-ribosyltransferase activity of cholera toxin and play a role in vesicular trafficking and as activators of phospholipase D. The gene products include 5 ARF proteins and 11 ARF-like proteins and constitute one family of the RAS superfamily. The ARF proteins are categorized as class I, class II and class III; this gene is a class II member. The members of each class share a common gene organization. The ARF4 gene spans approximately 12kb and contains six exons and five introns. This gene is the most divergent member of the human ARFs. Conflicting map positions at 3p14 or 3p21 have been reported for this gene. [provided by RefSeq, Jul 2008]
UniProt Comments for ARF4
ARF4: GTP-binding protein that functions as an allosteric activator of the cholera toxin catalytic subunit, an ADP- ribosyltransferase. Involved in protein trafficking; may modulate vesicle budding and uncoating within the Golgi apparatus. Belongs to the small GTPase superfamily. Arf family.

Protein type: Motility/polarity/chemotaxis; G protein; G protein, monomeric, ARF; G protein, monomeric

Chromosomal Location of Human Ortholog: 3p14.3

Cellular Component: Golgi apparatus; membrane; cytosol

Molecular Function: GTPase activity; protein binding; GTP binding; epidermal growth factor receptor binding

Biological Process: vesicle-mediated transport; epidermal growth factor receptor signaling pathway; phospholipase D activation; protein amino acid ADP-ribosylation; cell migration; protein transport; organelle organization and biogenesis; small GTPase mediated signal transduction; positive regulation of transcription from RNA polymerase II promoter; response to axon injury; brain development; negative regulation of apoptosis
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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