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anti-ASAP1 antibody :: Rabbit ASAP1 Polyclonal Antibody

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Catalog # MBS9609063
Unit / Price
  0.1 mL  /  $255 +1 FREE 8GB USB
  0.2 mL  /  $295 +1 FREE 8GB USB
Western Blot (WB)
Product Name

ASAP1, Polyclonal Antibody

Popular Item
Also Known As

ASAP1

Product Synonym Names
130 kDa phosphatidylinositol 4 5 biphosphate dependent ARF1 GTPase activating protein; 130 kDa phosphatidylinositol 4; 5-biphosphate-dependent ARF1 GTPase-activating protein; ADP ribosylation factor directed GTPase activating protein 1; ADP-ribosylation factor-directed GTPase-activating protein 1; AMAP 1; AMAP1; ANK repeat and PH domain-containing protein 1; ARF GTPase activating protein 1; ARF GTPase-activating protein 1; Arf-GAP with SH3 domain; ASAP 1; ASAP1; ASAP1_HUMAN; Centaurin beta 4; CentB4; DDEF 1; DDEF1 protein; DEF-1; Development and differentiation enhancing factor 1; Development and differentiation-enhancing factor 1; Differentiation-enhancing factor 1; KIAA1249; PAG 2; PAG2; PAP; PIP2 dependent ARF1 GAP; PIP2-dependent ARF1 GAP; ZG 14P; ZG14P
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence Length
1122
3D Structure
ModBase 3D Structure for Q9ULH1
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Specificity
ASAP1detects endogenous levels of total ASAP1
Purity/Purification
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.
Form/Format
Liquid
Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1mg/ml (lot specific)
Immunogen
A synthesized peptide derived from human ASAP1
Subcellular Location
Cytoplasm. Membrane. Predominantly Cytoplasmic (By similarity). Partially Membrane-Associated.
Conjugation
Unconjugated
Preparation and Storage
Store at -20 degree C. Stable for 12 months from date of receipt.
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Supply Chain Verification
Manufactured in a lab with traceable raw materials. Bulk orders can typically be prepared to the customer’s specifications, please inquire.
Other Notes
Small volumes of anti-ASAP1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-ASAP1 antibody
Function: Possesses phosphatidylinositol 4, 5-bisphosphate-dependent GTPase-activating protein activity for ARF1 (ADP ribosylation factor 1) and ARF5 and a lesser activity towards ARF6. May coordinate membrane trafficking with cell growth or actin cytoskeleton remodeling by binding to both SRC and PIP2. May function as a signal transduction protein involved in the differentiation of fibroblasts into adipocytes and possibly other cell types (By similarity). Plays a role in ciliogenesis.
Subunit Structure: Homodimer. Interacts with SRC and CRK. Interacts with RAB11FIP3. Interacts with PTK2B/PYK2 (By similarity). Interacts with CTTN. Interacts (via SH3 domain) with APC.
Post-translational Modifications: Phosphorylated on tyrosine residues by SRC.
Similarity: The PH domain most probably contributes to the phosphoinositide-dependent regulation of ADP ribosylation factors.
Applications Tested/Suitable for anti-ASAP1 antibody
Western Blot (WB), ELISA (EIA)
Application Notes for anti-ASAP1 antibody
WB: 1:1000-3000

Western Blot (WB) of anti-ASAP1 antibody
Western blot analysis of ASAP1 using Jurkat whole cell lysates
anti-ASAP1 antibody Western Blot (WB) (WB) image
NCBI/Uniprot data below describe general gene information for ASAP1. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
Observed: 125 kDa
Predicted: 126 kDa
NCBI Official Full Name
arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 isoform 2
NCBI Official Synonym Full Names
ArfGAP with SH3 domain, ankyrin repeat and PH domain 1
NCBI Official Symbol
ASAP1  [Similar Products]
NCBI Official Synonym Symbols
PAP; PAG2; AMAP1; DDEF1; ZG14P; CENTB4
  [Similar Products]
NCBI Protein Information
arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1
UniProt Protein Name
Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1
UniProt Synonym Protein Names
130 kDa phosphatidylinositol 4,5-bisphosphate-dependent ARF1 GTPase-activating protein; ADP-ribosylation factor-directed GTPase-activating protein 1; ARF GTPase-activating protein 1; Development and differentiation-enhancing factor 1; DEF-1; Differentiation-enhancing factor 1; PIP2-dependent ARF1 GAP
UniProt Gene Name
ASAP1  [Similar Products]
UniProt Synonym Gene Names
DDEF1; KIAA1249; ARF GTPase-activating protein 1; DEF-1; Differentiation-enhancing factor 1  [Similar Products]
NCBI Summary for ASAP1
This gene encodes an ADP-ribosylation factor (ARF) GTPase-activating protein. The GTPase-activating activity is stimulated by phosphatidylinositol 4,5-biphosphate (PIP2), and is greater towards ARF1 and ARF5, and lesser for ARF6. This gene maybe involved in regulation of membrane trafficking and cytoskeleton remodeling. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]
UniProt Comments for ASAP1
Possesses phosphatidylinositol 4,5-bisphosphate-dependent GTPase-activating protein activity for ARF1 (ADP ribosylation factor 1) and ARF5 and a lesser activity towards ARF6. May coordinate membrane trafficking with cell growth or actin cytoskeleton remodeling by binding to both SRC and PIP2. May function as a signal transduction protein involved in the differentiation of fibroblasts into adipocytes and possibly other cell types (). Plays a role in ciliogenesis.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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