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anti-ATP5A1 antibody :: Rabbit ATP synthase, H+ transportingF1 complex, alpha subunit 1, cardiac muscle Polyclonal Antibody

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Catalog # MBS710287
Unit / Price
  0.05 mL  /  $230 +1 FREE 8GB USB
  0.15 mL  /  $500 +1 FREE 8GB USB
anti-ATP5A1 antibody
Product Name

ATP synthase, H+ transportingF1 complex, alpha subunit 1, cardiac muscle (ATP5A1), Polyclonal Antibody

Also Known As

Rabbit anti-human ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle polyclonal Antibody

Product Synonym Names
ATP synthase; H+ transporting; mitochondrial F1 complex; alpha subunit 1; cardiac muscle; ATP5A1; ATP5A; ATP5AL2; ATPM; MOM2; OMR; ORM; hATP1
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence Length
553
OMIM
gene 615228
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Purity/Purification
Antigen Affinity Purified
Immunogen
Human ATP5A1
Storage Buffer
PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20 degree C, Avoid freeze / thaw cycles.
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-49162 / sc-49164 / sc-134728
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of anti-ATP5A1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for anti-ATP5A1 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
NCBI/Uniprot data below describe general gene information for ATP5A1. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
57,547 Da[Similar Products]
NCBI Official Full Name
ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle
NCBI Official Synonym Full Names
ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle
NCBI Official Symbol
ATP5A1  [Similar Products]
NCBI Official Synonym Symbols
OMR; ORM; ATPM; MOM2; ATP5A; hATP1; MC5DN4; ATP5AL2; COXPD22; HEL-S-123m
  [Similar Products]
NCBI Protein Information
ATP synthase subunit alpha, mitochondrial; ATP sythase (F1-ATPase) alpha subunit; ATP synthase alpha chain, mitochondrial; epididymis secretory sperm binding protein Li 123m; mitochondrial ATP synthetase, oligomycin-resistant; ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit, isoform 1, cardiac muscle; ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit, isoform 2, non-cardiac muscle-like 2
UniProt Protein Name
ATP synthase subunit alpha, mitochondrial
UniProt Gene Name
ATP5A1  [Similar Products]
UniProt Synonym Gene Names
ATP5A; ATP5AL2; ATPM  [Similar Products]
UniProt Entry Name
ATPA_HUMAN
NCBI Summary for ATP5A1
This gene encodes a subunit of mitochondrial ATP synthase. Mitochondrial ATP synthase catalyzes ATP synthesis, using an electrochemical gradient of protons across the inner membrane during oxidative phosphorylation. ATP synthase is composed of two linked multi-subunit complexes: the soluble catalytic core, F1, and the membrane-spanning component, Fo, comprising the proton channel. The catalytic portion of mitochondrial ATP synthase consists of 5 different subunits (alpha, beta, gamma, delta, and epsilon) assembled with a stoichiometry of 3 alpha, 3 beta, and a single representative of the other 3. The proton channel consists of three main subunits (a, b, c). This gene encodes the alpha subunit of the catalytic core. Alternatively spliced transcript variants encoding the different isoforms have been identified. Pseudogenes of this gene are located on chromosomes 9, 2, and 16. [provided by RefSeq, Mar 2012]
UniProt Comments for ATP5A1
ATP5A1: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Subunits alpha and beta form the catalytic core in F(1). Rotation of the central stalk against the surrounding alpha(3)beta(3) subunits leads to hydrolysis of ATP in three separate catalytic sites on the beta subunits. Subunit alpha does not bear the catalytic high-affinity ATP-binding sites. Belongs to the ATPase alpha/beta chains family.

Protein type: Energy Metabolism - oxidative phosphorylation; EC 3.6.3.14; Transporter; Membrane protein, integral; Mitochondrial; Hydrolase

Chromosomal Location of Human Ortholog: 18q21

Cellular Component: signalosome; membrane; mitochondrion; mitochondrial matrix; mitochondrial inner membrane; proton-transporting ATP synthase complex, catalytic core F(1); plasma membrane; mitochondrial proton-transporting ATP synthase complex

Molecular Function: protein binding; MHC class I protein binding; ATPase activity; hydrogen ion transporting ATP synthase activity, rotational mechanism; transmembrane transporter activity; hydrogen ion transporting ATPase activity, rotational mechanism; ATP binding

Biological Process: cellular metabolic process; embryonic development; ATP biosynthetic process; ATP hydrolysis coupled proton transport; negative regulation of endothelial cell proliferation; mitochondrial ATP synthesis coupled proton transport; lipid metabolic process

Disease: Combined Oxidative Phosphorylation Deficiency 22; Mitochondrial Complex V (atp Synthase) Deficiency, Nuclear Type 4
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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