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anti-ATP5J2 antibody :: Rabbit ATP5JL Polyclonal Antibody

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Catalog # MBS8231222
Unit / Price
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  0.03 mL  /  $155 +1 FREE 8GB USB
  0.1 mL  /  $220 +1 FREE 8GB USB
  0.2 mL  /  $295 +1 FREE 8GB USB
Product Name

ATP5JL (ATP5J2), Polyclonal Antibody

Popular Item
Full Product Name

Anti-ATP5JL Antibody

Product Synonym Names
ATP synthase f chain mitochondrial; ATP5JL; ATPK
Antibody/Peptide Pairs
ATP5JL peptide (MBS8231829) is used for blocking the activity of ATP5JL antibody (MBS8231222)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for P56134
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Specificity
Recognizes endogenous levels of ATP5JL protein.
Purity/Purification
The antibody was purified by immunogen affinity chromatography.
Form/Format
Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Immunogen
KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human ATP5JL. The exact sequence is proprietary.
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C for one year. Avoid freeze/thaw cycles.
Other Notes
Small volumes of anti-ATP5J2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-ATP5J2 antibody
Rabbit polyclonal antibody to ATP5JL
Applications Tested/Suitable for anti-ATP5J2 antibody
Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-ATP5J2 antibody
WB (1/500 - 1/1000), IHC (1/100 - 1/200)

Western Blot (WB) of anti-ATP5J2 antibody
Western blot analysis of ATP5JL expression in HEK293T (A), Raw264.7 (B), H9C2 (C) whole cell lysates.
anti-ATP5J2 antibody Western Blot (WB) (WB) image
Immunohistochemistry (IHC) of anti-ATP5J2 antibody
Immunohistochemical analysis of ATP5JL staining in human lung cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugad compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. w
anti-ATP5J2 antibody Immunohistochemistry (IHC) (IHC) image
NCBI/Uniprot data below describe general gene information for ATP5J2. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
ATP synthase subunit f, mitochondrial isoform 2b
NCBI Official Synonym Full Names
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F2
NCBI Official Symbol
ATP5J2  [Similar Products]
NCBI Official Synonym Symbols
ATP5JL
  [Similar Products]
NCBI Protein Information
ATP synthase subunit f, mitochondrial
UniProt Protein Name
ATP synthase subunit f, mitochondrial
UniProt Gene Name
ATP5J2  [Similar Products]
UniProt Synonym Gene Names
ATP5JL  [Similar Products]
UniProt Entry Name
ATPK_HUMAN
NCBI Summary for ATP5J2
Mitochondrial ATP synthase catalyzes ATP synthesis, utilizing an electrochemical gradient of protons across the inner membrane during oxidative phosphorylation. It is composed of two linked multi-subunit complexes: the soluble catalytic core, F1, and the membrane-spanning component, Fo, which comprises the proton channel. The catalytic portion of mitochondrial ATP synthase consists of five different subunits (alpha, beta, gamma, delta, and epsilon) assembled with a stoichiometry of 3 alpha, 3 beta, and single representatives of the gamma, delta, and epsilon subunits. The proton channel likely has nine subunits (a, b, c, d, e, f, g, F6 and 8). This gene encodes the f subunit of the Fo complex. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. This gene has multiple pseudogenes. Naturally occurring read-through transcription also exists between this gene and the downstream pentatricopeptide repeat domain 1 (PTCD1) gene. [provided by RefSeq, Nov 2010]
UniProt Comments for ATP5J2
ATP5J2: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. Minor subunit located with subunit a in the membrane. Belongs to the ATPase F chain family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Energy Metabolism - oxidative phosphorylation; Hydrolase; Mitochondrial

Chromosomal Location of Human Ortholog: 7q22.1

Cellular Component: proton-transporting ATP synthase complex, coupling factor F(o); mitochondrial inner membrane; integral to membrane; nucleus; mitochondrial proton-transporting ATP synthase complex

Molecular Function: ATPase activity; transmembrane transporter activity

Biological Process: cellular metabolic process; proton transport; mitochondrial ATP synthesis coupled proton transport
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Diseases associated with anti-ATP5J2 antibody
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