NP_001003805.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
14,667 Da
NCBI Official Full Name
ATP synthase subunit s, mitochondrial isoform b
NCBI Official Synonym Full Names
ATP synthase, H+ transporting, mitochondrial Fo complex subunit s (factor B)
NCBI Protein Information
ATP synthase subunit s, mitochondrial
UniProt Protein Name
ATP synthase subunit s, mitochondrial
UniProt Synonym Protein Names
ATP synthase-coupling factor B; FB; Mitochondrial ATP synthase regulatory component factor B
UniProt Synonym Gene Names
NCBI Summary for ATP5S
This gene encodes a subunit of mitochondrial ATP synthase. Mitochondrial ATP synthase catalyzes ATP synthesis, utilizing an electrochemical gradient of protons across the inner membrane during oxidative phosphorylation. ATP synthase is composed of two linked multi-subunit complexes: the soluble catalytic core, F1, and the membrane-spanning component, Fo, comprising the proton channel. This gene encodes the subunit s, also known as factor B, of the proton channel. This subunit is necessary for the energy transduction activity of the ATP synthase complexes. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
UniProt Comments for ATP5S
Involved in regulation of mitochondrial membrane ATP synthase. Necessary for H+ conduction of ATP synthase. Facilitates energy-driven catalysis of ATP synthesis by blocking a proton leak through an alternative proton exit pathway ().
Product References and Citations for anti-ATP5S antibody
(1) Ma, J., Dempsey, A.A., Stamatiou, D., et al. Identifying leukocyte gene expression patterns associated with plasma lipid levels in human subjects. Atherosclerosis 191 (1), 63-72 (2007).
Research Articles on ATP5S
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Pathways associated with anti-ATP5S antibody
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