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anti-AVPR1A antibody :: Rabbit AVPR1A Polyclonal Antibody

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Catalog # MBS176788
Unit / Price
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  0.1 mg  /  $280 +1 FREE 8GB USB
Western Blot (WB)
Product Name

AVPR1A, Polyclonal Antibody

Popular Item
Full Product Name

Anti-AVPR1A antibody

Product Synonym Names
Vasopressin V1a receptor; arginine vasopressin receptor 1A; Antidiuretic hormone receptor 1a antibody; Arginine vasopressin receptor 1A antibody; AVPR 1 antibody; AVPR 1A antibody; AVPR V1a antibody; AVPR1 antibody; AVPR1A antibody; SCCL vasopressin subtype 1a receptor antibody; V1 vascular vasopressin receptor AVPR1A antibody; V1a vasopressin receptor antibody; V1aR antibody; V1AR_HUMAN antibody; Vascular/hepatic type arginine vasopressin receptor antibody; Vascular/hepatic-type arginine vasopressin receptor antibody; Vasopressin V1a receptor antibody
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for P30560
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Reacts with: Human, Rat
Predicted to work with: Mouse
Specificity
No cross reactivity with other proteins.
Purity/Purification
Immunogen affinity purified.
Form/Format
Lyophilized
Immunogen
A synthetic peptide corresponding to a sequence in the middle region of rat AVPR1A (155-173aa HPLKTLQQPARRSRLMIAT), different from the related human and mouse sequences by one amino acid.
Contents
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
Reconstitution
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Preparation and Storage
At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen at -20 degree C for a longer time. Avoid repeated freezing and thawing.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of anti-AVPR1A antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-AVPR1A antibody
Description: Rabbit IgG polyclonal antibody for Vasopressin V1a receptor(AVPR1A) detection. Tested with WB in Human, Mouse, Rat.
Background: Arginine vasopressin receptor 1A(officially called AVPR1A) is one of the three major receptor types for arginine vasopressin (AVPR1B and AVPR2 being the others). It belongs to the subfamily of G-protein coupled receptors which includes AVPR1B, V2R and OXT receptors. This gene is mapped to 12q14.2. AVPR1A is present throughout the brain, as well as in the periphery, in the liver, kidney, and vasculature. The protein encoded by this gene acts as receptor for arginine vasopressin. Its activity is mediated by G proteins which stimulate a phosphatidylinositol-calcium second messenger system. The receptor mediates cell contraction and proliferation, platelet aggregation, release of coagulation factor and glycogenolysis.
Applications Tested/Suitable for anti-AVPR1A antibody
Western Blot (WB)
Application Notes for anti-AVPR1A antibody
Western Blot:
Concentration: 0.1-0.5ug/ml
Tested Species: Hu, Rat
Predicted Species: Ms

Tested Species: In-house tested species with positive results.
Predicted Species: Species predicted to be fit for the product based on sequence similarities.
Other applications have not been tested.
Optimal dilutions should be determined by end users.

Western Blot (WB) of anti-AVPR1A antibody
Anti-AVPR1A antibody, MBS176788, All Western blotting
All lanes: Anti-AVPR1A(MBS176788) at 0.5ug/ml
Lane 1: Rat Liver Tissue Lysate at 40ug
Lane 2: Rat Kidney Tissue Lysate at 40ug
Predicted bind size: 47KD
Observed bind size: 47KD
anti-AVPR1A antibody Western Blot (WB) (WB) image
NCBI/Uniprot data below describe general gene information for AVPR1A. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
47,655 Da
NCBI Official Full Name
Vasopressin V1a receptor
NCBI Official Synonym Full Names
arginine vasopressin receptor 1A
NCBI Official Symbol
Avpr1a  [Similar Products]
NCBI Official Synonym Symbols
V1a; AVPR; V1aR
  [Similar Products]
NCBI Protein Information
vasopressin V1a receptor; antidiuretic hormone receptor 1a; arginine vasopressin receptor V1a; vascular/hepatic-type arginine vasopressin receptor
UniProt Protein Name
Vasopressin V1a receptor
UniProt Synonym Protein Names
AVPR V1a; Antidiuretic hormone receptor 1a; Vascular/hepatic-type arginine vasopressin receptor
Protein Family
UniProt Gene Name
Avpr1a  [Similar Products]
UniProt Synonym Gene Names
UniProt Entry Name
V1AR_RAT
NCBI Summary for AVPR1A
This gene encodes a receptor for arginine vasopressin, a neurohypophyseal hormone involved in diuresis inhibition, smooth muscle contraction, liver glycogenolysis stimulation and regulation of adrenocorticotropic hormone release from the pituitary. This receptor represents one of three G protein-coupled arginine vasopressin receptors which functions through a phosphotidylinositol-calcium second messenger system in vascular and hepatic tissues. [provided by RefSeq, Jul 2008]
UniProt Comments for AVPR1A
AVPR1A: Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl- inositol-calcium second messenger system. Has been involved in social behaviors, including affiliation and attachment. Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily.

Protein type: Receptor, GPCR; Membrane protein, integral; Membrane protein, multi-pass; GPCR, family 1

Cellular Component: cytoplasmic vesicle membrane; integral to plasma membrane; integral to membrane; plasma membrane; cytoplasmic vesicle

Molecular Function: V1A vasopressin receptor binding; peptide hormone binding; vasopressin receptor activity

Biological Process: positive regulation of glutamate secretion; positive regulation of cellular pH reduction; positive regulation of systemic arterial blood pressure; cellular response to water deprivation; positive regulation of glycogen catabolic process; response to organic substance; elevation of cytosolic calcium ion concentration; positive regulation of cell proliferation; response to corticosterone stimulus; penile erection; positive regulation of prostaglandin biosynthetic process; grooming behavior; response to inorganic substance; maternal behavior; calcium-mediated signaling; myotube differentiation; positive regulation of heart rate; social behavior; positive regulation of cell growth; cellular response to hormone stimulus; negative regulation of female receptivity; G-protein coupled receptor protein signaling pathway; telencephalon development; regulation of systemic arterial blood pressure by vasopressin; negative regulation of transmission of nerve impulse; regulation of adrenocorticotropin hormone secretion; positive regulation of vasoconstriction; sperm ejaculation; positive regulation of blood pressure
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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