NP_001192.3
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
Observed: 53 kDa Predicted: 54 kDa
NCBI Official Full Name
bone morphogenetic protein 3 preproprotein
NCBI Official Synonym Full Names
bone morphogenetic protein 3
NCBI Official Synonym Symbols
NCBI Protein Information
bone morphogenetic protein 3
UniProt Protein Name
Bone morphogenetic protein 3
UniProt Synonym Protein Names
Bone morphogenetic protein 3A; BMP-3A; Osteogenin
UniProt Synonym Gene Names
NCBI Summary for BMP3
This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein suppresses osteoblast differentiation, and negatively regulates bone density, by modulating TGF-beta receptor availability to other ligands. [provided by RefSeq, Jul 2016]
UniProt Comments for BMP3
Negatively regulates bone density. Antagonizes the ability of certain osteogenic BMPs to induce osteoprogenitor differentitation and ossification.
Research Articles on BMP3
Precautions
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Disclaimer
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Products associated with anti-BMP3 antibody
Pathways associated with anti-BMP3 antibody
Diseases associated with anti-BMP3 antibody
Organs/Tissues associated with anti-BMP3 antibody
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