NP_665810.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
Observed: 31 kDa Predicted: 31 kDa
NCBI Official Full Name
voltage-dependent calcium channel gamma-5 subunit
NCBI Official Synonym Full Names
calcium voltage-gated channel auxiliary subunit gamma 5
NCBI Protein Information
voltage-dependent calcium channel gamma-5 subunit
UniProt Protein Name
Voltage-dependent calcium channel gamma-5 subunit
UniProt Synonym Protein Names
Neuronal voltage-gated calcium channel gamma-5 subunit; Transmembrane AMPAR regulatory protein gamma-5; TARP gamma-5
UniProt Synonym Gene Names
NCBI Summary for CACNG5
The protein encoded by this gene is a type II transmembrane AMPA receptor regulatory protein (TARP). TARPs regulate both trafficking and channel gating of the AMPA receptors. This gene is part of a functionally diverse eight-member protein subfamily of the PMP-22/EMP/MP20 family and is located in a cluster with two family members, a type I TARP and a calcium channel gamma subunit. This gene is a susceptibility locus for schizophrenia and bipolar disorder. [provided by RefSeq, Dec 2010]
UniProt Comments for CACNG5
Regulates the gating properties of AMPA-selective glutamate receptors (AMPARs). Modulates their gating properties by accelerating their rates of activation, deactivation and desensitization. Displays subunit-specific AMPA receptor regulation. Shows specificity for GRIA1, GRIA4 and the long isoform of GRIA2. Thought to stabilize the calcium channel in an inactivated (closed) state ().
Research Articles on CACNG5
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Pathways associated with anti-CACNG5 antibody
Organs/Tissues associated with anti-CACNG5 antibody
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