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anti-CAPRIN1 antibody :: Rabbit CAPRIN1 Polyclonal Antibody

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Catalog # MBS9603240
Unit / Price
  0.1 mL  /  $255 +1 FREE 8GB USB
  0.2 mL  /  $295 +1 FREE 8GB USB
Product Name

CAPRIN1, Polyclonal Antibody

Popular Item
Full Product Name

CAPRIN1 Antibody

Product Synonym Names
activation/proliferation-associated protein 1; CAPR1_HUMAN; Caprin-1; CAPRIN1; Cell cycle-associated protein 1; Cytoplasmic activation-and proliferation-associated protein 1; cytoplasmic activation/proliferation-associated protein-1; GPI-anchored membrane protein 1; GPI-anchored protein p137; GPI-p137; GPIAP1; M11S1; Membrane component chromosome 11 surface marker 1; p137GPI; RNA granule protein 105; RNG105
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for Q14444
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Specificity
CAPRIN1 antibody detects endogenous levels of CAPRIN1.
Purity/Purification
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.
Form/Format
Liquid
Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1mg/ml (lot specific)
Immunogen
A synthesized peptide derived from human CAPRIN1.
Subcellular Location
Cytoplasm > Cytosol. Cell Projection > Dendrite. Associated with RNA granules.
Tissue Specificity
Ubiquitous.
Conjugation
Unconjugated
Preparation and Storage
Store at -20 degree C. Stable for 12 months from date of receipt.
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Supply Chain Verification
Manufactured in a lab with traceable raw materials manufactured on site. Coordinated product portfolio of antibodies, pairs, conjugates, recombinant proteins, and immunoassay materials available, please inquire.
Other Notes
Small volumes of anti-CAPRIN1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-CAPRIN1 antibody
Function: May regulate the transport and translation of mRNAs of proteins involved in synaptic plasticity in neurons and cell proliferation and migration in multiple cell types. Binds directly and selectively to MYC and CCND2 RNAs. In neuronal cells, directly binds to several mRNAs associated with RNA granules, including BDNF, CAMK2A, CREB1, MAP2, NTRK2 mRNAs, as well as to GRIN1 and KPNB1 mRNAs, but not to rRNAs.
Subunit Structure: May form homomultimers (By similarity). Interacts with G3BP1; interaction is direct and takes place in cytoplasmic RNA granules (PubMed:17210633). Interacts with PQBP1 (PubMed:21933836).
Post-translational Modifications: O-glycosylated (O-GlcNAcylated), in a cell cycle-dependent manner.
Similarity: Belongs to the caprin family.
Applications Tested/Suitable for anti-CAPRIN1 antibody
Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-CAPRIN1 antibody
WB: 1:500-1:2000
IHC: 1:50-1:200

Immunohistochemistry (IHC) of anti-CAPRIN1 antibody
MBS9603240 at 1/100 staining Human breast cancer tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22 degree C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
anti-CAPRIN1 antibody Immunohistochemistry (IHC) (IHC) image
Western Blot (WB) of anti-CAPRIN1 antibody
Western blot analysis of extracts of HeLa and ND7 cells, using CAPRIN1 antibody.
anti-CAPRIN1 antibody Western Blot (WB) (WB) image
NCBI/Uniprot data below describe general gene information for CAPRIN1. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
Observed: 116 kD
Predicted: 79 kDa
NCBI Official Full Name
caprin-1 isoform 1
NCBI Official Synonym Full Names
cell cycle associated protein 1
NCBI Official Symbol
CAPRIN1  [Similar Products]
NCBI Official Synonym Symbols
M11S1; GPIAP1; RNG105; GPIP137; GRIP137; p137GPI
  [Similar Products]
NCBI Protein Information
caprin-1
UniProt Protein Name
Caprin-1
UniProt Synonym Protein Names
Cell cycle-associated protein 1; Cytoplasmic activation- and proliferation-associated protein 1; GPI-anchored membrane protein 1; GPI-anchored protein p137; GPI-p137; p137GPI; Membrane component chromosome 11 surface marker 1; RNA granule protein 105
Protein Family
UniProt Gene Name
CAPRIN1  [Similar Products]
UniProt Synonym Gene Names
GPIAP1; GPIP137; M11S1; RNG105; GPI-p137; p137GPI  [Similar Products]
UniProt Comments for CAPRIN1
May regulate the transport and translation of mRNAs of proteins involved in synaptic plasticity in neurons and cell proliferation and migration in multiple cell types. Binds directly and selectively to MYC and CCND2 RNAs. In neuronal cells, directly binds to several mRNAs associated with RNA granules, including BDNF, CAMK2A, CREB1, MAP2, NTRK2 mRNAs, as well as to GRIN1 and KPNB1 mRNAs, but not to rRNAs.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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