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anti-CAPRIN2 antibody :: Rabbit CAPRIN2 Polyclonal Antibody

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Catalog # MBS2516464
Unit / Price
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  0.06 mL  /  $195 +1 FREE 8GB USB
  0.12 mL  /  $270 +1 FREE 8GB USB
  0.2 mL  /  $435 +1 FREE 8GB USB
Product Name

CAPRIN2, Polyclonal Antibody

Popular Item
Full Product Name

CAPRIN2 Antibody

Product Synonym Names
C1QDC1, caprin 2, caprin family member 2, CAPRIN2, EEG 1, EEG1, KIAA1873, Protein EEG1, RNA granule protein 140, RNG140
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
MBS2516464 Technical Datasheet
OMIM
610375
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Purity/Purification
Antigen affinity purification
Immunogen
Fusion protein of CAPRIN2
Buffer
PBS with 0.02% sodium azide and 50% glycerol pH7.3.
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-107473 / sc-107474
Calculated MW
1127aa,126 kDa
Observed MW
150 kDa
Preparation and Storage
Store at -20 degree C. Avoid freeze / thaw cycles
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Other Notes
Small volumes of anti-CAPRIN2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-CAPRIN2 antibody
Promotes phosphorylation of the Wnt coreceptor LRP6, leading to increased activity of the canonical Wnt signaling pathway (PubMed:18762581). Faciliates constitutive LRP6 phosphorylation by CDK14/CCNY during G2/M stage of the cell cycle, which may potentiate cells for Wnt signaling (PubMed:27821587). May regulate the transport and translation of mRNAs, modulating for instance the expression of proteins involved in synaptic plasticity in neurons (By similarity). Involved in regulation of growth as erythroblasts shift from a highly proliferative state towards their terminal phase of differentiation (PubMed:14593112). May be involved in apoptosis (PubMed:14593112).
Applications Tested/Suitable for anti-CAPRIN2 antibody
ELISA (EIA), Western Blot (WB), Immunofluorescence (IF)
Application Notes for anti-CAPRIN2 antibody
WB 1:200-1:1000, IF 1:20-1:200

Western Blot of anti-CAPRIN2 antibody
SH-SY5Y cells were subjected to SDS-PAGE followed by western blot with CAPRIN2 Polyclonal Antibody at dilution of 1:300
anti-CAPRIN2 antibody Western Blot (WB) image
Immunofluorescent of anti-CAPRIN2 antibody
Immunofluorescent analysis of HepG2 cells using CAPRIN2 Polyclonal Antibody at dilution of 1:50 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
anti-CAPRIN2 antibody Immunofluorescent image
NCBI/Uniprot data below describe general gene information for CAPRIN2. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
caprin-2 isoform 4
NCBI Official Synonym Full Names
caprin family member 2
NCBI Official Symbol
CAPRIN2  [Similar Products]
NCBI Official Synonym Symbols
EEG1; EEG-1; C1QDC1; RNG140
  [Similar Products]
NCBI Protein Information
caprin-2; C1q domain-containing protein 1; CAPRIN2; RNA granule protein 140; cytoplasmic activation/proliferation-associated protein 2; gastric cancer multidrug resistance-associated protein
UniProt Protein Name
Caprin-2
UniProt Synonym Protein Names
C1q domain-containing protein 1; Cytoplasmic activation/proliferation-associated protein 2; Gastric cancer multidrug resistance-associated protein; Protein EEG-1; RNA granule protein 140
Protein Family
UniProt Gene Name
CAPRIN2  [Similar Products]
UniProt Entry Name
CAPR2_HUMAN
NCBI Summary for CAPRIN2
The protein encoded by this gene may be involved in the transitioning of erythroblasts from a highly proliferative state to a terminal phase of differentiation. High level expression of the encoded protein can lead to apoptosis. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2011]
UniProt Comments for CAPRIN2
C1QDC1: May regulate the transport and translation of mRNAs, modulating for instance the expression of proteins involved in synaptic plasticity in neurons. Involved in regulation of growth as erythroblasts shift from a highly proliferative state towards their terminal phase of differentiation. May be involved in apoptosis. Belongs to the caprin family. 9 isoforms of the human protein are produced by alternative splicing.

Protein type: Unknown function

Chromosomal Location of Human Ortholog: 12p11

Cellular Component: nucleoplasm; centrosome; mitochondrion; cytoplasm; nucleus; receptor complex

Molecular Function: protein binding; RNA binding; receptor binding

Biological Process: positive regulation of protein binding; negative regulation of translation; positive regulation of transcription from RNA polymerase II promoter; positive regulation of dendrite morphogenesis; negative regulation of cell growth; positive regulation of peptidyl-serine phosphorylation
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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