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anti-CCL11 antibody :: Rabbit CCL11 Polyclonal Antibody

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Catalog # MBS9608810
Unit / Price
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  0.1 mL  /  $255 +1 FREE 8GB USB
  0.2 mL  /  $295 +1 FREE 8GB USB
Product Name

CCL11, Polyclonal Antibody

Popular Item
Full Product Name

CCL11 Antibody

Product Synonym Names
C-C motif chemokine 11; CCL 11; CCL11; CCL11_HUMAN; chemokine (C-C motif) ligand 11; Chemokine C C motif ligand 11; Chemokine CC Motif Ligand 11; Chemokine ligand 11; Eosinophil chemotactic protein; Eotaxin; eotaxin-1; MGC22554; SCYA 11; SCYA11; Small inducible cytokine A11; Small inducible cytokine subfamily A (Cys Cys) member 11; small inducible cytokine subfamily A (Cys-Cys), member 11 (eotaxin); Small inducible cytokine subfamily A member 11; Small-inducible cytokine A11
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for P51671
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Specificity
CCL11 antibody detects endogenous levels of total CCL11
Purity/Purification
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.
Form/Format
Liquid
Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1mg/ml (lot specific)
Immunogen
A synthesized peptide derived from human CCL11
Subcellular Location
Secreted.
Tissue Specificity
Induced by TNF, IL1A/interleukin-1 alpha and IFNG/IFN-gamma.
Predicted Cross Reactivity
Horse, Rabbit
Similarity
Horse (80%), Rabbit (90%)
Conjugation
Unconjugated
Preparation and Storage
Store at -20 degree C. Stable for 12 months from date of receipt.
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Supply Chain Verification
Manufactured in a lab with traceable raw materials manufactured on site. Coordinated product portfolio of antibodies, pairs, conjugates, recombinant proteins, and immunoassay materials available, please inquire.
Other Notes
Small volumes of anti-CCL11 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-CCL11 antibody
Function: In response to the presence of allergens, this protein directly promotes the accumulation of eosinophils, a prominent feature of allergic inflammatory reactions. Binds to CCR3.
Post-translational Modifications: O-linked glycan consists of a Gal-GalNAc disaccharide which is modified with up to 2 sialic acid residues.
Similarity: Belongs to the intercrine beta (chemokine CC) family.
Applications Tested/Suitable for anti-CCL11 antibody
Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA)
Application Notes for anti-CCL11 antibody
WB: 1:1000-3000
IHC: 1:200

Immunohistochemistry (IHC) of anti-CCL11 antibody
MBS9608810 at 1/100 staining Human Melanoma tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22 degree C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
anti-CCL11 antibody Immunohistochemistry (IHC) (IHC) image
Western Blot (WB) of anti-CCL11 antibody
Western blot analysis of CCL11 using lung whole tissue lysates
anti-CCL11 antibody Western Blot (WB) (WB) image
NCBI/Uniprot data below describe general gene information for CCL11. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
Observed: 18 kDa
Predicted: 11 kDa
NCBI Official Full Name
eotaxin
NCBI Official Synonym Full Names
C-C motif chemokine ligand 11
NCBI Official Symbol
CCL11  [Similar Products]
NCBI Official Synonym Symbols
SCYA11
  [Similar Products]
NCBI Protein Information
eotaxin
UniProt Protein Name
Eotaxin
UniProt Synonym Protein Names
C-C motif chemokine 11; Eosinophil chemotactic protein; Small-inducible cytokine A11
Protein Family
UniProt Gene Name
CCL11  [Similar Products]
UniProt Synonym Gene Names
SCYA11  [Similar Products]
NCBI Summary for CCL11
This antimicrobial gene is one of several chemokine genes clustered on the q-arm of chromosome 17. Chemokines form a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of the N-terminal cysteine residues of the mature peptide. This chemokine, a member of the CC subfamily, displays chemotactic activity for eosinophils, but not mononuclear cells or neutrophils. This eosinophil-specific chemokine is thought to be involved in eosinophilic inflammatory diseases such as atopic dermatitis, allergic rhinitis, asthma and parasitic infections. [provided by RefSeq, Sep 2014]
UniProt Comments for CCL11
In response to the presence of allergens, this protein directly promotes the accumulation of eosinophils, a prominent feature of allergic inflammatory reactions. Binds to CCR3.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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