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anti-CD54 antibody :: Rabbit CD54 (ICAM1) Polyclonal Antibody

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Catalog # MBS551030
Unit / Price
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  0.1 mg  /  $280 +1 FREE 8GB USB
  0.2 mg  /  $385 +1 FREE 8GB USB
Immunohistochemistry
Product Name

CD54 (ICAM1), Polyclonal Antibody

Popular Item
Full Product Name

Rabbit anti CD54 (ICAM1) Polyclonal

Product Synonym Names
Rabbit anti Human CD54 Polyclonal purified; icam1; icam-1; cd54; cd-54; polyclonal; PAb
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for P13597
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Purity/Purification
>95%
Purification:Serum IgG fraction was purified by Protein G affinity chromatography.
Form/Format
Lyophilized from 0.2um filtered solution in PBS pH 7.4.
Source Note
Polyclonal CD54 (ICAM1) antibody was produced from sera of rabbits immunized with synthetic protein containing CD54 antigenic determinants.
Reconstitution
A quick spin of the vial followed by reconstitution in 0.01M PBS pH 7.4 or other dilutents.
Preparation and Storage
The lyophilized antibody is stable for at least 1 year from date of receipt at -20 degree C.
Upon reconstitution, this antibody can be stored in working aliquots at 2 degree - 8 degree C for one month, or at -20 degree C for six months without detectable loss of activity.

Avoid repeated freeze/thaw cycles.
Shelf Life: >12 months
Other Notes
Small volumes of anti-CD54 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Product Categories/Family for anti-CD54 antibody
Applications Tested/Suitable for anti-CD54 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC).
Application Notes for anti-CD54 antibody
ELISA: Use at a concentration range of 1-2 ug/ml.
WB: Use at a concentration range of 2-10 ug/ml.
IHC: A suitable range of concentrations of this antibody for IHC is 2-10 ug/ml.

Immunohistochemistry of anti-CD54 antibody
anti-CD54 antibody Immunohistochemistry (IHC) image
NCBI/Uniprot data below describe general gene information for CD54. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
58,844 Da
NCBI Official Full Name
intercellular adhesion molecule 1
UniProt Protein Name
Intercellular adhesion molecule 1
UniProt Synonym Protein Names
MALA-2; MyD10
UniProt Gene Name
Icam1  [Similar Products]
UniProt Synonym Gene Names
Icam-1; ICAM-1  [Similar Products]
UniProt Entry Name
ICAM1_MOUSE
UniProt Comments for CD54
ICAM1: a type I membrane protein of the immunoglobulin superfamily. Is a ligand for the leukocyte adhesion LFA-1 protein (Integrin alpha-L/beta-2) and a Rhinovirus receptor. Typically expressed on endothelial cells and cells of the immune system. ICAM1 binds to integrins of type CD11a / CD18, or CD11b / CD18. Its expression is activated by p53 in an NF-kappaB-independent manner. Induced by TNFalpha in a process that involves IKKbeta.

Protein type: Immunoglobulin superfamily; Membrane protein, integral; Cell adhesion

Cellular Component: extracellular space; focal adhesion; cell surface; membrane; integral to plasma membrane; integral to membrane; plasma membrane; immunological synapse; external side of plasma membrane; lipid raft

Molecular Function: integrin binding; protein complex binding

Biological Process: regulation of cell adhesion; virion attachment, binding of host cell surface receptor; negative regulation of calcium ion transport; positive regulation of nitric oxide biosynthetic process; T cell antigen processing and presentation; activation of NF-kappaB transcription factor; positive regulation of cellular extravasation; regulation of cell shape; positive regulation of peptidyl-tyrosine phosphorylation; cell-cell adhesion; leukocyte adhesion; sensory perception of sound; positive regulation of actin filament polymerization; T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell; positive regulation of vasoconstriction; adhesion to host; cell adhesion mediated by integrin; cell adhesion; acute inflammatory response to antigenic stimulus

Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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