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anti-CD66 antibody :: Rabbit CD66c (CEACAM6) Polyclonal Antibody

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Catalog # MBS551035
Unit / Price
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  0.1 mg  /  $375 +1 FREE 8GB USB
  0.2 mg  /  $495 +1 FREE 8GB USB
anti-CD66 antibody
Product Name

CD66c (CEACAM6), Polyclonal Antibody

Popular Item
Full Product Name

Rabbit anti Human CD66c (CEACAM6) Polyclonal

Product Synonym Names
Rabbit anti Human CD66c (CEACAM6) Polyclonal purified; cd66c; cd-66c; cd-66; cd66; CEACAM6; polyclonal; PAb
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
OMIM
114890
3D Structure
ModBase 3D Structure for P06731
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Purity/Purification
Serum IgG fraction was purified by Protein A affinity chromatography.
Form/Format
0.2 um filtered solution in PBS with 5% trehalose.
Source Note
Polyclonal CD66c antibody was produced from sera of rabbits immunized with recombinant human CD66c.
Reconstitution
A quick spin of the vial followed by reconstitution in distilled water. This solution can then be diluted into other buffers.
Preparation and Storage
The lyophilized antibody is stable for at least 1 year from date of receipt at -20 degree C.
Upon reconstitution, this antibody can be stored in working aliquots at 2 degree - 8 degree C for one month, or at -20 degree C for six months without detectable loss of activity.

Avoid repeated freeze/thaw cycles.
Shelf Life: >12 months
Other Notes
Small volumes of anti-CD66 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Product Categories/Family for anti-CD66 antibody
Applications Tested/Suitable for anti-CD66 antibody
ELISA (EIA)
Application Notes for anti-CD66 antibody
ELISA: Use at a concentration range of 0.5-1ug/ml. The detection limit for CEACAM6 is approximately 0.16 ng/well.
NCBI/Uniprot data below describe general gene information for CD66. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Related Accession #
Molecular Weight
76,795 Da
NCBI Official Full Name
carcinoembryonic antigen-related cell adhesion molecule 5 preproprotein
UniProt Protein Name
Carcinoembryonic antigen-related cell adhesion molecule 5
UniProt Synonym Protein Names
Carcinoembryonic antigen; CEA; Meconium antigen 100
UniProt Gene Name
CEACAM5  [Similar Products]
UniProt Synonym Gene Names
CEA; CEA  [Similar Products]
UniProt Entry Name
CEAM5_HUMAN
NCBI Summary for CD66
This gene encodes a cell surface glycoprotein that represents the founding member of the carcinoembryonic antigen (CEA) family of proteins. The encoded protein is used as a clinical biomarker for gastrointestinal cancers and may promote tumor development through its role as a cell adhesion molecule. Additionally, the encoded protein may regulate differentiation, apoptosis, and cell polarity. This gene is present in a CEA family gene cluster on chromosome 19. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2015]
UniProt Comments for CD66
CEACAM5: Cell surface glycoprotein that plays a role in cell adhesion and in intracellular signaling. Receptor for E.coli Dr adhesins. Homodimer. Binding of E.coli Dr adhesins leads to dissociation of the homodimer. Found in adenocarcinomas of endodermally derived digestive system epithelium and fetal colon. Belongs to the immunoglobulin superfamily. CEA family.

Protein type: Membrane protein, integral; Immunoglobulin superfamily; Membrane protein, GPI anchor

Chromosomal Location of Human Ortholog: 19q13.1-q13.2

Cellular Component: integral to plasma membrane; basolateral plasma membrane

Molecular Function: identical protein binding; protein homodimerization activity

Biological Process: homotypic cell-cell adhesion; negative regulation of apoptosis
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Products associated with anti-CD66 antibody
 Reference Product  PubMed Publications
 HNRNPM antibody  >2 publications with CD66 and HNRNPM
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