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anti-CHST1 antibody :: Rabbit CHST1 Polyclonal Antibody

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Catalog # MBS7051861
Unit / Price
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  0.05 mg  /  $160 +1 FREE 8GB USB
  0.1 mg  /  $235 +1 FREE 8GB USB
Product Name

CHST1, Polyclonal Antibody

Popular Item
Full Product Name

CHST1 Antibody

Product Synonym Names
Carbohydrate sulfotransferase 1; Galactose/N-acetylglucosamine/N-acetylglucosamine 6-O-sulfotransferase 1; GST-1; Keratan sulfate Gal-6 sulfotransferase; KS6ST; KSGal6ST; KSST; CHST1
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
OMIM
AB003791 mRNA
3D Structure
ModBase 3D Structure for O43916
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Purity/Purification
>95%, Protein G purified
Form/Format
Liquid
Immunogen
Recombinant Human Carbohydrate sulfotransferase 1 protein (305-397AA)
Conjugation
Non-conjugated
Preservative
0.03% Proclin 300
Constituents
50% Glycerol, 0.01M PBS, pH 7.4
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of anti-CHST1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-CHST1 antibody
Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the transfer of sulfate to position 6 of galactose (Gal) residues of keratan. Has a preference for sulfating keratan sulfate, but it also transfers sulfate to the unsulfated polymer. The sulfotransferase activity on sialyl LacNAc structures is much higher than the corresponding desialylated substrate, and only internal Gal residues are sulfated. May function in the sulfation of sialyl N-acetyllactosamine oligosaccharide chains attached to glycoproteins. Participates in biosynthesis of selectin ligands. Selectin ligands are present in high endothelial cells (HEVs) and play a central role in lymphocyte homing at sites of inflammation.
Applications Tested/Suitable for anti-CHST1 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-CHST1 antibody
WB: 1:500-1:5000
IHC: 1:20-1:200

Western Blot (WB) of anti-CHST1 antibody
Western Blot
Positive WB detected in: HL-60 whole cell lysate,Mouse brain tissue,Rat heart tissue
All lanes: CHST1 antibody at 3ug/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 47 KDa
Observed band size: 47 KDa

anti-CHST1 antibody Western Blot (WB) (WB) image
Immunohistochemistry (IHC) of anti-CHST1 antibody
Immunohistochemistry of paraffin-embedded human brain tissue using MBS7051861 at dilution of 1:100
anti-CHST1 antibody Immunohistochemistry (IHC) (IHC) image
NCBI/Uniprot data below describe general gene information for CHST1. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
46,715 Da
NCBI Official Full Name
carbohydrate sulfotransferase 1
NCBI Official Synonym Full Names
carbohydrate sulfotransferase 1
NCBI Official Symbol
CHST1  [Similar Products]
NCBI Official Synonym Symbols
C6ST; KSST; GST-1; KS6ST; KSGal6ST
  [Similar Products]
NCBI Protein Information
carbohydrate sulfotransferase 1
UniProt Protein Name
Carbohydrate sulfotransferase 1
UniProt Synonym Protein Names
Galactose/N-acetylglucosamine/N-acetylglucosamine 6-O-sulfotransferase 1; GST-1; Keratan sulfate Gal-6 sulfotransferase; KS6ST; KSGal6ST; KSST
UniProt Gene Name
CHST1  [Similar Products]
UniProt Synonym Gene Names
GST-1; KS6ST; KSGal6ST; KSST  [Similar Products]
NCBI Summary for CHST1
This locus encodes a member of the keratin sulfotransferase family of proteins. The encoded enzyme catalyzes the sulfation of the proteoglycan keratin. [provided by RefSeq, Aug 2011]
UniProt Comments for CHST1
CHST1: Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the transfer of sulfate to position 6 of galactose (Gal) residues of keratan. Has a preference for sulfating keratan sulfate, but it also transfers sulfate to the unsulfated polymer. The sulfotransferase activity on sialyl LacNAc structures is much higher than the corresponding desialylated substrate, and only internal Gal residues are sulfated. May function in the sulfation of sialyl N- acetyllactosamine oligosaccharide chains attached to glycoproteins. Participates in biosynthesis of selectin ligands. Selectin ligands are present in high endothelial cells (HEVs) and play a central role in lymphocyte homing at sites of inflammation. Belongs to the sulfotransferase 1 family. Gal/GlcNAc/GalNAc subfamily.

Protein type: EC 2.8.2.21; Glycan Metabolism - keratan sulfate biosynthesis; Membrane protein, integral; Transferase

Chromosomal Location of Human Ortholog: 11p11.2

Cellular Component: Golgi membrane

Molecular Function: keratan sulfotransferase activity; N-acetylglucosamine 6-O-sulfotransferase activity; sulfotransferase activity

Biological Process: galactose metabolic process; keratan sulfate biosynthetic process; keratan sulfate metabolic process; polysaccharide metabolic process; sulfur metabolic process
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Diseases associated with anti-CHST1 antibody
Organs/Tissues associated with anti-CHST1 antibody
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