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anti-CKMT2 antibody :: Rabbit CKMT2 Polyclonal Antibody

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Catalog # MBS9128475
Unit / Price
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  0.05 mL  /  $200 +1 FREE 8GB USB
  0.1 mL  /  $275 +1 FREE 8GB USB
  0.2 mL  /  $430 +1 FREE 8GB USB
Product Name

CKMT2, Polyclonal Antibody

Popular Item
Full Product Name

CKMT2 Polyclonal Antibody

Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
OMIM
123295
3D Structure
ModBase 3D Structure for P17540
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Purity/Purification
Affinity Purification
Immunogen
Recombinant Protein
Immunogen
Recombinant protein of human CKMT2
Preparation and Storage
Store at -20 degree C. Avoid freeze / thaw cycles.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Other Notes
Small volumes of anti-CKMT2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-CKMT2 antibody
Mitochondrial creatine kinase (MtCK) is responsible for the transfer of high energy phosphate from mitochondria to the cytosolic carrier, creatine. It belongs to the creatine kinase isoenzyme family. It exists as two isoenzymes, sarcomeric MtCK and ubiquitous MtCK, encoded by separate genes. Mitochondrial creatine kinase occurs in two different oligomeric forms: dimers and octamers, in contrast to the exclusively dimeric cytosolic creatine kinase isoenzymes. Sarcomeric mitochondrial creatine kinase has 80% homology with the coding exons of ubiquitous mitochondrial creatine kinase. This gene contains sequences homologous to several motifs that are shared among some nuclear genes encoding mitochondrial proteins and thus may be essential for the coordinated activation of these genes during mitochondrial biogenesis. Three transcript variants encoding the same protein have been found for this gene.
Applications Tested/Suitable for anti-CKMT2 antibody
Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-CKMT2 antibody
WB 1:500 - 1:2000
IHC 1:20 - 1:200

Western Blot (WB) of anti-CKMT2 antibody
Western blot analysis of extracts of various cell lines, using CKMT2 antibody at 1:1000 dilution.
Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (MBS128200) at 1:10000 dilution.
Lysates/proteins: 25ug per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit.
Exposure time: 1s.
anti-CKMT2 antibody Western Blot (WB) (WB) image
Immunohistochemistry (IHC) of anti-CKMT2 antibody
Immunohistochemistry of paraffin-embedded rat heart using CKMT2 antibody at dilution of 1:100 (40x lens).
anti-CKMT2 antibody Immunohistochemistry (IHC) (IHC) image
Immunohistochemistry (IHC) of anti-CKMT2 antibody
Immunohistochemistry of paraffin-embedded human esophagus using CKMT2 antibody at dilution of 1:100 (40x lens).
anti-CKMT2 antibody Immunohistochemistry (IHC) (IHC) image
Immunohistochemistry (IHC) of anti-CKMT2 antibody
Immunohistochemistry of paraffin-embedded mouse heart using CKMT2 antibody at dilution of 1:100 (40x lens).
anti-CKMT2 antibody Immunohistochemistry (IHC) (IHC) image
NCBI/Uniprot data below describe general gene information for CKMT2. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
48kDa
NCBI Official Full Name
creatine kinase S-type, mitochondrial
NCBI Official Synonym Full Names
creatine kinase, mitochondrial 2 (sarcomeric)
NCBI Official Symbol
CKMT2  [Similar Products]
NCBI Official Synonym Symbols
SMTCK
  [Similar Products]
NCBI Protein Information
creatine kinase S-type, mitochondrial
UniProt Protein Name
Creatine kinase S-type, mitochondrial
UniProt Synonym Protein Names
Basic-type mitochondrial creatine kinase; Mib-CK; Sarcomeric mitochondrial creatine kinase; S-MtCK
Protein Family
UniProt Gene Name
CKMT2  [Similar Products]
UniProt Synonym Gene Names
Mib-CK; S-MtCK  [Similar Products]
UniProt Entry Name
KCRS_HUMAN
NCBI Summary for CKMT2
Mitochondrial creatine kinase (MtCK) is responsible for the transfer of high energy phosphate from mitochondria to the cytosolic carrier, creatine. It belongs to the creatine kinase isoenzyme family. It exists as two isoenzymes, sarcomeric MtCK and ubiquitous MtCK, encoded by separate genes. Mitochondrial creatine kinase occurs in two different oligomeric forms: dimers and octamers, in contrast to the exclusively dimeric cytosolic creatine kinase isoenzymes. Sarcomeric mitochondrial creatine kinase has 80% homology with the coding exons of ubiquitous mitochondrial creatine kinase. This gene contains sequences homologous to several motifs that are shared among some nuclear genes encoding mitochondrial proteins and thus may be essential for the coordinated activation of these genes during mitochondrial biogenesis. Three transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
UniProt Comments for CKMT2
CKMT2: Reversibly catalyzes the transfer of phosphate between ATP and various phosphogens (e.g. creatine phosphate). Creatine kinase isoenzymes play a central role in energy transduction in tissues with large, fluctuating energy demands, such as skeletal muscle, heart, brain and spermatozoa. Belongs to the ATP:guanido phosphotransferase family.

Protein type: Mitochondrial; Amino Acid Metabolism - arginine and proline; Kinase, other; EC 2.7.3.2

Chromosomal Location of Human Ortholog: 5q13.3

Cellular Component: mitochondrion; mitochondrial inner membrane

Molecular Function: creatine kinase activity; ATP binding

Biological Process: muscle contraction; creatine metabolic process; phosphorylation
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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