• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

anti-CLDN18 antibody :: Rabbit CLDN18 Polyclonal Antibody

Scan QR to view Datasheet
Catalog # MBS9609709
Unit / Price
Scan QR to view Datasheet
  0.1 mL  /  $255 +1 FREE 8GB USB
  0.2 mL  /  $295 +1 FREE 8GB USB
Western Blot (WB)
Product Name

CLDN18, Polyclonal Antibody

Popular Item
Full Product Name

CLDN18 Antibody

Product Synonym Names
Claudin 18; Claudin-18; CLD18_HUMAN; CLDN18; SFTA5; SFTPJ
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for P56856
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Specificity
CLDN18 antibody detects endogenous levels of total CLDN18
Purity/Purification
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.
Form/Format
Liquid
Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1mg/ml (lot specific)
Immunogen
A synthesized peptide derived from human CLDN18
Subcellular Location
Cell Junction > Tight Junction. Cell Membrane.
Tissue Specificity
Concentrated at the cell-cell borders of epithelial cells.
Predicted Cross Reactivity
Pig, Bovine, Horse, Sheep, Rabbit
Similarity
Pig (82%), Bovine (83%), Horse (100%), Sheep (92%), Rabbit (92%)
Conjugation
Unconjugated
Preparation and Storage
Store at -20 degree C. Stable for 12 months from date of receipt.
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Supply Chain Verification
Manufactured in a lab with traceable raw materials manufactured on site. Coordinated product portfolio of antibodies, pairs, conjugates, recombinant proteins, and immunoassay materials available, please inquire.
Other Notes
Small volumes of anti-CLDN18 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-CLDN18 antibody
Function: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
Similarity: Belongs to the claudin family.
Applications Tested/Suitable for anti-CLDN18 antibody
Western Blot (WB), ELISA (EIA)
Application Notes for anti-CLDN18 antibody
WB: 1:1000-3000

Western Blot (WB) of anti-CLDN18 antibody
Western blot analysis of CLDN18 using Jurkat whole cell lysates
anti-CLDN18 antibody Western Blot (WB) (WB) image
NCBI/Uniprot data below describe general gene information for CLDN18. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
Observed: 28 kDa
Predicted: 28 kDa
NCBI Official Full Name
claudin-18 isoform 2
NCBI Official Synonym Full Names
claudin 18
NCBI Official Symbol
CLDN18  [Similar Products]
NCBI Official Synonym Symbols
SFTA5; SFTPJ
  [Similar Products]
NCBI Protein Information
claudin-18
UniProt Protein Name
Claudin-18
Protein Family
UniProt Gene Name
CLDN18  [Similar Products]
NCBI Summary for CLDN18
This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. This gene is upregulated in patients with ulcerative colitis and highly overexpressed in infiltrating ductal adenocarcinomas. PKC/MAPK/AP-1 (protein kinase C/mitogen-activated protein kinase/activator protein-1) dependent pathway regulates the expression of this gene in gastric cells. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jun 2010]
UniProt Comments for CLDN18
Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000