• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

anti-C1S antibody :: Rabbit complement component 1, s subcomponent Polyclonal Antibody

Scan QR to view Datasheet
Catalog # MBS713165
Unit / Price
  0.05 mL  /  $230 +1 FREE 8GB USB
  0.15 mL  /  $500 +1 FREE 8GB USB
anti-C1S antibody
Product Name

complement component 1, s subcomponent (C1S), Polyclonal Antibody

Also Known As

Rabbit anti-human complement component 1, s subcomponent polyclonal Antibody

Product Synonym Names
complement component 1; s subcomponent; C1S; FLJ44757
Product Gene Name
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence Length
688
OMIM
gene 613783
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Purity/Purification
Antigen Affinity Purified
Immunogen
Human C1S
Storage Buffer
PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20 degree C, Avoid freeze / thaw cycles.
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of anti-C1S antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for anti-C1S antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
NCBI/Uniprot data below describe general gene information for C1S. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
76,684 Da[Similar Products]
NCBI Official Full Name
Complement component 1, s subcomponent
NCBI Official Synonym Full Names
complement component 1, s subcomponent
NCBI Official Symbol
NCBI Protein Information
complement C1s subcomponent; C1 esterase; basic proline-rich peptide IB-1; complement component 1 subcomponent s
UniProt Protein Name
Complement C1s subcomponent
UniProt Synonym Protein Names
C1 esterase; Complement component 1 subcomponent sCleaved into the following 2 chains:Complement C1s subcomponent heavy chain; Complement C1s subcomponent light chain
UniProt Gene Name
UniProt Entry Name
C1S_HUMAN
NCBI Summary for C1S
This gene encodes a serine protease, which is a major constituent of the human complement subcomponent C1. C1s associates with two other complement components C1r and C1q in order to yield the first component of the serum complement system. Defects in this gene are the cause of selective C1s deficiency. [provided by RefSeq, Mar 2009]
UniProt Comments for C1S
C1S: C1s B chain is a serine protease that combines with C1q and C1r to form C1, the first component of the classical pathway of the complement system. C1r activates C1s so that it can, in turn, activate C2 and C4. Defects in C1S are the cause of complement component C1s deficiency (C1SD). A rare defect resulting in C1 deficiency and impaired activation of the complement classical pathway. C1 deficiency generally leads to severe immune complex disease with features of systemic lupus erythematosus and glomerulonephritis. Belongs to the peptidase S1 family.

Protein type: EC 3.4.21.42; Protease

Chromosomal Location of Human Ortholog: 12p13

Cellular Component: extracellular region

Molecular Function: identical protein binding; protein binding; serine-type endopeptidase activity; calcium ion binding

Biological Process: innate immune response; proteolysis; complement activation, classical pathway; complement activation

Disease: Complement Component C1s Deficiency
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000