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anti-CRNN antibody :: Rabbit CRNN Polyclonal Antibody

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Catalog # MBS1493743
Unit / Price
  0.05 mg  /  $160 +1 FREE 8GB USB
  0.1 mg  /  $235 +1 FREE 8GB USB
Western Blot (WB)
Product Name

CRNN, Polyclonal Antibody

Popular Item
Full Product Name

CRNN Antibody

Product Synonym Names
Cornulin; CRNN; C1orf10; DRC1; PDRC1; SEP53; 53 kDa putative calcium-binding protein; 53 kDa squamous epithelial-induced stress protein; 58 kDa heat shock protein; Squamous epithelial heat shock protein 53; Tumor-related protein
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
OMIM
611312
3D Structure
ModBase 3D Structure for Q9UBG3
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Purity/Purification
>95%, Protein G Purified
Storage Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Conjugate
Non-conjugated
Immunogen
Recombinant human Cornulin protein
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-164097
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of anti-CRNN antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-CRNN antibody
Survival factor that participates in the clonogenicity of squamous esophageal epithelium cell lines, attenuates deoxycholic acid (DCA)-induced apoptotic cell death and release of calcium. When overexpressed in oral squamous carcinom cell lines, regulates negatively cell proliferation by the induction of G1 arrest.
Applications Tested/Suitable for anti-CRNN antibody
ELISA (EIA), Western Blot (WB)
Application Notes for anti-CRNN antibody
Recommended dilution: WB:1:500-2000

Western Blot (WB) of anti-CRNN antibody
Western blot
All lanes: CRNN antibody at 12ug/ml
Lane 1:HepG2 whole cell lysate
Lane 2:Mouse heart tissue
Lane 3:rat skeletal muscle tissue
Secondary
Goat polyclonal to rabbit at 1/10000 dilution
Predicted band size: 54kDa
Observed band size: 54kDa

anti-CRNN antibody Western Blot (WB) (WB) image
NCBI/Uniprot data below describe general gene information for CRNN. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
53,533 Da
NCBI Official Full Name
cornulin
NCBI Official Synonym Full Names
cornulin
NCBI Official Symbol
NCBI Official Synonym Symbols
DRC1; PDRC1; SEP53; C1orf10
  [Similar Products]
NCBI Protein Information
cornulin
UniProt Protein Name
Cornulin
UniProt Synonym Protein Names
53 kDa putative calcium-binding protein; 53 kDa squamous epithelial-induced stress protein; 58 kDa heat shock protein; Squamous epithelial heat shock protein 53; Tumor-related protein
Protein Family
UniProt Gene Name
UniProt Synonym Gene Names
C1orf10; DRC1; PDRC1; SEP53  [Similar Products]
UniProt Entry Name
CRNN_HUMAN
NCBI Summary for CRNN
This gene encodes a member of the "fused gene" family of proteins, which contain N-terminus EF-hand domains and multiple tandem peptide repeats. The encoded protein contains two EF-hand Ca2+ binding domains in its N-terminus and two glutamine- and threonine-rich 60 amino acid repeats in its C-terminus. This gene, also known as squamous epithelial heat shock protein 53, may play a role in the mucosal/epithelial immune response and epidermal differentiation. [provided by RefSeq, Jan 2009]
UniProt Comments for CRNN
CRNN: Survival factor that participates in the clonogenicity of squamous esophageal epithelium cell lines, attenuates deoxycholic acid (DCA)-induced apoptotic cell death and release of calcium. When overexpressed in oral squamous carcinom cell lines, regulates negatively cell proliferation by the induction of G1 arrest. Belongs to the S100-fused protein family.

Chromosomal Location of Human Ortholog: 1q21

Cellular Component: cytoplasm; membrane

Molecular Function: calcium ion binding

Biological Process: cell-cell adhesion; response to heat
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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