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anti-CRYBB3 antibody :: Rabbit crystallin, beta B3 Polyclonal Antibody

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Catalog # MBS711067
Unit / Price
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  0.05 mL  /  $230 +1 FREE 8GB USB
  0.15 mL  /  $500 +1 FREE 8GB USB
anti-CRYBB3 antibody
Product Name

crystallin, beta B3 (CRYBB3), Polyclonal Antibody

Full Product Name

Rabbit anti-human crystallin, beta B3 polyclonal Antibody

Product Synonym Names
crystallin; beta B3; CRYBB3; CATCN2; CRYB3; MGC125772; MGC125773; MGC125774Beta-B3 crystallin; Beta-crystallin B3
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
OMIM
gene 609741
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Purity/Purification
Antigen Affinity Purified
Immunogen
Human CRYBB3
Storage Buffer
PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20 degree C, Avoid freeze / thaw cycles.
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-22412 / sc-22413
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of anti-CRYBB3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for anti-CRYBB3 antibody
ELISA (EIA), Western Blot (WB), Immunofluorescence (IF)
NCBI/Uniprot data below describe general gene information for CRYBB3. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
24,252 Da[Similar Products]
NCBI Official Full Name
Crystallin, beta B3
NCBI Official Synonym Full Names
crystallin, beta B3
NCBI Official Symbol
CRYBB3  [Similar Products]
NCBI Official Synonym Symbols
CRYB3; CATCN2; CTRCT22
  [Similar Products]
NCBI Protein Information
beta-crystallin B3; eye lens structural protein
UniProt Protein Name
Beta-crystallin B3
UniProt Synonym Protein Names
Beta-B3 crystallinCleaved into the following chain:Beta-crystallin B3, N-terminally processed
Protein Family
UniProt Gene Name
CRYBB3  [Similar Products]
UniProt Synonym Gene Names
CRYB3  [Similar Products]
UniProt Entry Name
CRBB3_HUMAN
NCBI Summary for CRYBB3
Crystallins are separated into two classes: taxon-specific, or enzyme, and ubiquitous. The latter class constitutes the major proteins of vertebrate eye lens and maintains the transparency and refractive index of the lens. Since lens central fiber cells lose their nuclei during development, these crystallins are made and then retained throughout life, making them extremely stable proteins. Mammalian lens crystallins are divided into alpha, beta, and gamma families; beta and gamma crystallins are also considered as a superfamily. Alpha and beta families are further divided into acidic and basic groups. Seven protein regions exist in crystallins: four homologous motifs, a connecting peptide, and N- and C-terminal extensions. Beta-crystallins, the most heterogeneous, differ by the presence of the C-terminal extension (present in the basic group, none in the acidic group). Beta-crystallins form aggregates of different sizes and are able to self-associate to form dimers or to form heterodimers with other beta-crystallins. This gene, a beta basic group member, is part of a gene cluster with beta-A4, beta-B1, and beta-B2. Mutations in this gene result in cataract congenital nuclear autosomal recessive type 2. [provided by RefSeq, Feb 2013]
UniProt Comments for CRYBB3
CRYBB3: a major structural protein of the eye lens. A member of the beta/gamma-crystallin family.

Protein type: Cytoskeletal

Chromosomal Location of Human Ortholog: 22q11.23

Molecular Function: structural constituent of eye lens

Biological Process: visual perception

Disease: Cataract 22, Multiple Types
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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