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anti-CS061 antibody :: Rabbit CS061 Polyclonal Antibody

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Catalog # MBS9609187
Unit / Price
  0.1 mL  /  $255 +1 FREE 8GB USB
  0.2 mL  /  $295 +1 FREE 8GB USB
Western Blot (WB)
Product Name

CS061, Polyclonal Antibody

Popular Item
Also Known As

CS061 Antibody

Product Synonym Names
Chromosome 19 open reading frame 61; DKFZp564H1322; F17127_1; FLJ12886; Protein smg 9 homolog; Protein smg-9 homolog; Protein SMG9; SMG 9; smg9; SMG9_HUMAN; Suppressor with morphogenetic effect on genitalia protein 9,
Product Synonym Gene Name
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence Length
520
3D Structure
ModBase 3D Structure for Q9H0W8
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Specificity
CS061 antibody detects endogenous levels of total CS061
Purity/Purification
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.
Form/Format
Liquid
Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1mg/ml (lot specific)
Immunogen
A synthesized peptide derived from human CS061
Conjugation
Unconjugated
Preparation and Storage
Store at -20 degree C. Stable for 12 months from date of receipt.
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Supply Chain Verification
Manufactured in a lab with traceable raw materials. Bulk orders can typically be prepared to the customer’s specifications, please inquire.
Other Notes
Small volumes of anti-CS061 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-CS061 antibody
Function: Involved in nonsense-mediated decay (NMD) of mRNAs containing premature stop codons (PubMed:19417104). Is recruited by release factors to stalled ribosomes together with SMG1 and SMG8 (forming the SMG1C protein kinase complex) and, in the SMG1C complex, is required for the efficient association between SMG1 and SMG8 (PubMed:19417104). Plays a role in brain, heart, and eye development (By similarity).
Subunit Structure: Component of the SMG1C complex composed of SMG1, SMG8 and SMG9. Self-associates to form homodimers and forms heterodimers with SMG8; these assembly forms may represent SMG1C intermediate forms.
Post-translational Modifications: Phosphorylated by SMG1.
Similarity: Belongs to the SMG9 family.
Applications Tested/Suitable for anti-CS061 antibody
Western Blot (WB), ELISA (EIA)
Application Notes for anti-CS061 antibody
WB: 1:1000-3000

Western Blot (WB) of anti-CS061 antibody
Western blot analysis of CS061 using HuvEc whole cell lysates
anti-CS061 antibody Western Blot (WB) (WB) image
NCBI/Uniprot data below describe general gene information for CS061. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
Observed: 58 kDa
Predicted: 58 kDa
NCBI Official Full Name
protein SMG9
NCBI Official Synonym Full Names
SMG9, nonsense mediated mRNA decay factor
NCBI Official Symbol
NCBI Official Synonym Symbols
HBMS; C19orf61; F17127_1
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NCBI Protein Information
protein SMG9
UniProt Protein Name
Protein SMG9
UniProt Synonym Protein Names
Protein SMG-9
UniProt Gene Name
NCBI Summary for CS061
This gene encodes a regulatory subunit of the SMG1 complex, which plays a critical role in nonsense-mediated mRNA decay (NMD). Binding of the encoded protein to the SMG1 complex kinase scaffold protein results in the inhibition of its kinase activity. Mutations in this gene cause a multiple congenital anomaly syndrome in human patients, characterized by brain malformation, congenital heart disease and other features. [provided by RefSeq, Jul 2016]
UniProt Comments for CS061
Involved in nonsense-mediated decay (NMD) of mRNAs containing premature stop codons (PubMed:19417104). Is recruited by release factors to stalled ribosomes together with SMG1 and SMG8 (forming the SMG1C protein kinase complex) and, in the SMG1C complex, is required for the efficient association between SMG1 and SMG8 (PubMed:19417104). Plays a role in brain, heart, and eye development ().
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

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