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anti-CSF2RB antibody :: Rabbit CSF2RB / CD131 Polyclonal Antibody

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Catalog # MBS247912
Unit / Price
  0.05 mL  /  $530 +1 FREE 8GB USB
Product Name

CSF2RB / CD131, Polyclonal Antibody

Popular Item
Also Known As

Rabbit Polyclonal (IgG) to Human CSF2RB / CD131

Product Synonym Names
Anti-CSF2RB / CD131 Antibody (aa559-608) IHC-plus; CSF2RB; CD131 antigen; CDw131; IL3RB; IL5RB; SMDP5; CD131; GM-CSF receptor beta chain; Human CSF2RB; CD131
Product Synonym Gene Name
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence Length
897
OMIM
gene 614370
3D Structure
ModBase 3D Structure for P32927
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Specificity
IL-3R beta antibody detects endogenous levels of total IL-3R beta protein.
Purity/Purification
Immunoaffinity Purified
Form/Format
PBS (without Mg2+, Ca2+), pH 7.4, 150 mM sodium chloride, 0.02% sodium azide, 50% glycerol
Concentration
1 mg/ml (lot specific)
Target Species
Human
Immunogen Description
Synthetic peptide from human IL-3R beta (aa559-608).
Immunogen
CSF2RB / CD131 antibody was raised against synthetic peptide from human IL-3R beta (aa559-608).
Antigen Modification
aa559-608
Preparation and Storage
Short term 4 degree C, long term aliquot and store at -20 degree C, avoid freeze thaw cycles.
Other Notes
Small volumes of anti-CSF2RB antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-CSF2RB antibody
CSF2RB is a common beta chain of the high affinity receptor for IL-3, IL-5 and CSF. Defective CSF2RB has been reported to be associated with protein alveolar proteinosis.
Applications Tested/Suitable for anti-CSF2RB antibody
Immunohistochemistry (IHC - Paraffin), Western Blot (WB), ELISA (EIA)
Application Notes for anti-CSF2RB antibody
ELISA (1:1000), IHC-P (10 ug/ml), WB (1:500 - 1:1000)

Immunohistochemistry (IHC) of anti-CSF2RB antibody
Anti-CSF2RB / CD131 antibody IHC of human spleen, neutrophils. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
anti-CSF2RB antibody Immunohistochemistry (IHC) (IHC) image
Western Blot (WB) of anti-CSF2RB antibody
Western blot of extracts from Raw264.7 cells, treated with G-CSF 25 ng/ml 15', using IL-3R beta antibody. The lane on the right is treated with the synthesized peptide.
anti-CSF2RB antibody Western Blot (WB) (WB) image
NCBI/Uniprot data below describe general gene information for CSF2RB. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
97,976 Da
NCBI Official Full Name
cytokine receptor common subunit beta
NCBI Official Synonym Full Names
colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)
NCBI Official Symbol
CSF2RB  [Similar Products]
NCBI Official Synonym Symbols
CD131; IL3RB; IL5RB; SMDP5; CDw131
  [Similar Products]
NCBI Protein Information
cytokine receptor common subunit beta; GM-CSF/IL-3/IL-5 receptor common beta-chain; GM-CSF/IL-3/IL-5 receptor common beta subunit; colony-stimulating factor-2 receptor, beta, low-affinity; interleukin 3 receptor/granulocyte-macrophage colony stimulating factor 3 receptor, beta (high affinity)
UniProt Protein Name
Cytokine receptor common subunit beta
UniProt Synonym Protein Names
CDw131; GM-CSF/IL-3/IL-5 receptor common beta subunit; CD_antigen: CD131
Protein Family
UniProt Gene Name
CSF2RB  [Similar Products]
UniProt Synonym Gene Names
IL3RB; IL5RB  [Similar Products]
UniProt Entry Name
IL3RB_HUMAN
NCBI Summary for CSF2RB
The protein encoded by this gene is the common beta chain of the high affinity receptor for IL-3, IL-5 and CSF. Defects in this gene have been reported to be associated with protein alveolar proteinosis (PAP). [provided by RefSeq, Jul 2008]
UniProt Comments for CSF2RB
CSF2RB: a common beta chain of the high affinity receptor for IL-3, IL-5 and CSF. A type I cytokine family of receptor. Defects are a cause of congenital pulmonary alveolar proteinosis (PAP) [MIM:265120]. PAP is an autosomal recessive fatal respiratory disease.

Protein type: Membrane protein, integral; Receptor, cytokine

Chromosomal Location of Human Ortholog: 22q13.1

Cellular Component: granulocyte macrophage colony-stimulating factor receptor complex; integral to plasma membrane; plasma membrane

Molecular Function: protein binding; interleukin-5 receptor activity; interleukin-3 receptor activity; receptor activity

Biological Process: response to lipopolysaccharide; respiratory gaseous exchange; signal transduction

Disease: Surfactant Metabolism Dysfunction, Pulmonary, 5
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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