• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

anti-DAO antibody :: Goat D-amino-acid oxidase Polyclonal Antibody

Scan QR to view Datasheet
Catalog # MBS421015
Unit / Price
Scan QR to view Datasheet
  0.1 mg  /  $300 +1 FREE 8GB USB
anti-DAO antibody
Product Name

D-amino-acid oxidase (DAO), Polyclonal Antibody

Full Product Name

Goat anti-D-amino-acid oxidase Antibody

Product Synonym Names
Goat Anti-D-amino-acid oxidase (aa286-298) Antibody; DAO; D-amino-acid oxidase; DAAO; DAMOX; MGC35381; OXDA; DAO antibody; D-amino-acid oxidase antibody; DAAO antibody; DAMOX antibody; MGC35381 antibody; OXDA antibody; D-amino-acid oxidase; D-amino-acid oxidase
Product Gene Name
Antibody/Peptide Pairs
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence
EEKKLSRMPP SH
OMIM
124050
Clonality
Polyclonal
Host
Goat
Species Reactivity
Expected from sequence similarity: Human, Rat, Mouse
Purity/Purification
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Form/Format
Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Concentration
100ug specific antibody in 200ul (lot specific)
Immunogen
Peptide with sequence C-EEKKLSRMPPSH, from the C Terminus of the protein sequence according to NP_001908.3.
Epitope
C Terminus
Preparation and Storage
Aliquot and store at -20 degree C. Minimize freezing and thawing.
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of anti-DAO antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for anti-DAO antibody
Peptide ELISA (EIA)
Application Notes for anti-DAO antibody
Peptide ELISA: Antibody detection limit dilution 1: 64000.
Western Blot: Preliminary experiments in human brain (cerebellum, hippocampus, substantia nigra) lysates gave no specific signal but low background (at antibody concentration up to 1ug/ml).
NCBI/Uniprot data below describe general gene information for DAO. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
39,474 Da
NCBI Official Full Name
D-amino-acid oxidase
NCBI Official Synonym Full Names
D-amino-acid oxidase
NCBI Official Symbol
NCBI Official Synonym Symbols
DAAO; OXDA; DAMOX
  [Similar Products]
NCBI Protein Information
D-amino-acid oxidase
UniProt Protein Name
D-amino-acid oxidase
Protein Family
UniProt Gene Name
UniProt Synonym Gene Names
DAMOX; DAAO; DAMOX; DAO  [Similar Products]
UniProt Entry Name
OXDA_HUMAN
NCBI Summary for DAO
This gene encodes the peroxisomal enzyme D-amino acid oxidase. The enzyme is a flavoprotein which uses flavin adenine dinucleotide (FAD) as its prosthetic group. Its substrates include a wide variety of D-amino acids, but it is inactive on the naturally occurring L-amino acids. Its biological function is not known; it may act as a detoxifying agent which removes D-amino acids that accumulate during aging. In mice, it degrades D-serine, a co-agonist of the NMDA receptor. This gene may play a role in the pathophysiology of schizophrenia. [provided by RefSeq, Jul 2008]
UniProt Comments for DAO
DAO: Regulates the level of the neuromodulator D-serine in the brain. Has high activity towards D-DOPA and contributes to dopamine synthesis. Could act as a detoxifying agent which removes D-amino acids accumulated during aging. Acts on a variety of D- amino acids with a preference for those having small hydrophobic side chains followed by those bearing polar, aromatic, and basic groups. Does not act on acidic amino acids. Belongs to the DAMOX/DASOX family.

Protein type: Amino Acid Metabolism - arginine and proline; Amino Acid Metabolism - glycine, serine and threonine; Other Amino Acids Metabolism - D-Arginine and D-ornithine; EC 1.4.3.3; Oxidoreductase

Chromosomal Location of Human Ortholog: 12q24

Cellular Component: cytosol; mitochondrial outer membrane; peroxisomal matrix; peroxisomal membrane; peroxisome

Molecular Function: cofactor binding; D-amino-acid oxidase activity; protein binding; protein dimerization activity; receptor binding

Biological Process: dopamine biosynthetic process; glyoxylate metabolic process; proline catabolic process

Disease: Schizophrenia
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000