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anti-DVL3 antibody :: Rabbit Dishevelled 3 Polyclonal Antibody

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Catalog # MBS821860
Unit / Price
  0.03 mL  /  $155 +1 FREE 8GB USB
  0.1 mL  /  $220 +1 FREE 8GB USB
  0.2 mL  /  $295 +1 FREE 8GB USB
anti-DVL3 antibody
Product Name

Dishevelled 3 (DVL3), Polyclonal Antibody

Popular Item
Full Product Name

Anti-Dishevelled 3 Antibody

Product Synonym Names
KIAA0208; Segment polarity protein dishevelled homolog DVL-3; Dishevelled-3; DSH homolog 3
Antibody/Peptide Pairs
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
OMIM
601368
3D Structure
ModBase 3D Structure for Q92997
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Specificity
Recognizes endogenous levels of Dishevelled 3 protein.
Purity/Purification
The antibody was purified by immunogen affinity chromatography.
Form/Format
Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Immunogen
KLH-conjugated synthetic peptide encompassing a sequence within the center region of human Dishevelled 3. The exact sequence is proprietary.
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C for one year. Avoid freeze/thaw cycles.
Other Notes
Small volumes of anti-DVL3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-DVL3 antibody
Rabbit polyclonal antibody to Dishevelled 3
Applications Tested/Suitable for anti-DVL3 antibody
Western Blot (WB)
Application Notes for anti-DVL3 antibody
WB (1/500 - 1/1000)

Western Blot (WB) of anti-DVL3 antibody
anti-DVL3 antibody Western Blot (WB) (WB) image
NCBI/Uniprot data below describe general gene information for DVL3. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
76,256 Da
NCBI Official Full Name
segment polarity protein dishevelled homolog DVL-3
NCBI Official Synonym Full Names
dishevelled segment polarity protein 3
NCBI Official Symbol
NCBI Protein Information
segment polarity protein dishevelled homolog DVL-3; DSH homolog 3; dishevelled-3; dishevelled, dsh homolog 3; dishevelled 3 (homologous to Drosophila dsh)
UniProt Protein Name
Segment polarity protein dishevelled homolog DVL-3
UniProt Synonym Protein Names
DSH homolog 3
UniProt Gene Name
UniProt Synonym Gene Names
KIAA0208; Dishevelled-3  [Similar Products]
UniProt Entry Name
DVL3_HUMAN
NCBI Summary for DVL3
This gene is a member of a multi-gene family which shares strong similarity with the Drosophila dishevelled gene, dsh. The Drosophila dishevelled gene encodes a cytoplasmic phosphoprotein that regulates cell proliferation. [provided by RefSeq, Jul 2008]
UniProt Comments for DVL3
DVL3: a protein in the WNT/planar cell polarity (PCP) signaling pathway. Dvl2-deficient mice indicate that Dvl2 is essential for normal cardiac morphogenesis, somite segmentation and neural tube closure. Transduces the Wnt signal by interacting with the cytoplasmic Axin complex. Dvl and Axin each contain a DIX domains, which mediate their dynamic polymerization. The Dvl-Axin interaction is essential for Wnt signaling. Interacts through its PDZ domain with the C-terminal regions of VANGL1 and VANGL2. Interacts with Dixin and Rac. There is functional redundancy between Dvl1 and Dvl2 in some phenotypes.

Protein type: Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 3q27

Cellular Component: cytosol

Molecular Function: protein binding; protease binding; frizzled binding; protein heterodimerization activity; beta-catenin binding; receptor binding

Biological Process: response to drug; positive regulation of JNK activity; Wnt receptor signaling pathway; Wnt receptor signaling pathway, planar cell polarity pathway; positive regulation of transcription, DNA-dependent; positive regulation of protein amino acid phosphorylation; Wnt receptor signaling pathway through beta-catenin
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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