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anti-DLL1 antibody :: Goat DLL1 Polyclonal Antibody

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Catalog # MBS422082
Unit / Price
  0.1 mg  /  $300 +1 FREE 8GB USB
Western Blot (WB)
Product Name

DLL1, Polyclonal Antibody

Full Product Name

Goat anti-DLL1 Antibody

Product Synonym Names
DLL1; delta-like 1 (Drosophila); DELTA1; DL1; Delta; OTTHUMP00000017690; delta (Drosophila)-like 1; delta-like 1; delta-like 1 protein; DLL1 antibody; delta-like 1 (Drosophila) antibody; DELTA1 antibody; DL1 antibody; Delta antibody; OTTHUMP00000017690 antibody; delta (Drosophila)-like 1 antibody; delta-like 1 antibody; delta-like 1 protein antibody
Antibody/Peptide Pairs
DLL1 peptide (MBS425938) is used for blocking the activity of DLL1 antibody (MBS422082)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence
ATQRHLTVGE EWSQD
OMIM
606582
Clonality
Polyclonal
Host
Goat
Species Reactivity
Tested: Mouse, Rat; Expected from sequence similarity: Human, Mouse, Rat
Purity/Purification
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Form/Format
Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Concentration
100ug specific antibody in 200ul (lot specific)
Immunogen
Peptide with sequence C-ATQRHLTVGEEWSQD, from the internal region of the protein sequence according to NP_005609.3.
Epitope
Internal region
Preparation and Storage
Aliquot and store at -20 degree C. Minimize freezing and thawing.
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Other Notes
Small volumes of anti-DLL1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for anti-DLL1 antibody
Peptide ELISA (EIA), Western Blot (WB)
Application Notes for anti-DLL1 antibody
Peptide ELISA: Antibody detection limit dilution 1: 16000.
Western Blot: Approx.75kDa band observed in Mouse Heart and Rat Heart lysates (calculated MW of 78.1kDa according to Human NP_005609.3, 78.5kDa according to Mouse NP_031891.2 and 77.4kDa according to Rat NP_114452.1). Recommended concentration: 0.3-1ug/ml.

Western Blot (WB) of anti-DLL1 antibody
(0.3ug/ml) staining of Rat Heart lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
anti-DLL1 antibody Western Blot (WB) (WB) image
NCBI/Uniprot data below describe general gene information for DLL1. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
27,355 Da
NCBI Official Full Name
delta-like protein 1
NCBI Official Synonym Full Names
delta like canonical Notch ligand 1
NCBI Official Symbol
NCBI Official Synonym Symbols
DL1; Delta; DELTA1
  [Similar Products]
NCBI Protein Information
delta-like protein 1
UniProt Protein Name
Delta-like protein 1
UniProt Synonym Protein Names
Drosophila Delta homolog 1; Delta1; H-Delta-1
Protein Family
UniProt Gene Name
UniProt Synonym Gene Names
Delta1; H-Delta-1  [Similar Products]
UniProt Entry Name
DLL1_HUMAN
NCBI Summary for DLL1
DLL1 is a human homolog of the Notch Delta ligand and is a member of the delta/serrate/jagged family. It plays a role in mediating cell fate decisions during hematopoiesis. It may play a role in cell-to-cell communication. [provided by RefSeq, Jul 2008]
UniProt Comments for DLL1
DLL1: Acts as a ligand for Notch receptors. Blocks the differentiation of progenitor cells into the B-cell lineage while promoting the emergence of a population of cells with the characteristics of a T-cell/NK-cell precursor. Interacts with Notch receptors. Expressed in heart and pancreas, with lower expression in brain and muscle and almost no expression in placenta, lung, liver and kidney.

Protein type: Cell development/differentiation; Motility/polarity/chemotaxis; Membrane protein, integral

Chromosomal Location of Human Ortholog: 6q27

Cellular Component: adherens junction; apical plasma membrane; cytoplasmic vesicle; extracellular region; integral to plasma membrane; lipid raft; plasma membrane

Molecular Function: calcium ion binding; Notch binding; protein binding; Tat protein binding

Biological Process: astrocyte development; cell differentiation; cell fate determination; cerebellar molecular layer formation; cerebellar Purkinje cell layer structural organization; compartment specification; determination of left/right symmetry; heart looping; hemopoiesis; inner ear development; lateral inhibition; marginal zone B cell differentiation; negative regulation of auditory receptor cell differentiation; negative regulation of cell differentiation; negative regulation of cell proliferation; negative regulation of epidermal cell differentiation; negative regulation of epithelial cell differentiation; negative regulation of interleukin-10 production; negative regulation of myeloid cell differentiation; negative regulation of myoblast differentiation; negative regulation of neuron differentiation; neuron fate specification; Notch receptor processing; Notch signaling pathway; organ growth; positive regulation of cell proliferation; positive regulation of endocytosis; positive regulation of Notch signaling pathway; positive regulation of skeletal muscle growth; positive regulation of transcription from RNA polymerase II promoter; proximal/distal pattern formation; regulation of blood pressure; regulation of cell adhesion; regulation of cell division; regulation of growth; regulation of neurogenesis; regulation of skeletal muscle growth; regulation of somitogenesis; retina development in camera-type eye; retina morphogenesis in camera-type eye; skeletal muscle growth; somite specification; somitogenesis; spinal cord development
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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