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anti-DNAJB11 antibody :: Rabbit DNAJB11 Polyclonal Antibody

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Catalog # MBS821509
Unit / Price
  0.03 mL  /  $155 +1 FREE 8GB USB
  0.1 mL  /  $220 +1 FREE 8GB USB
  0.2 mL  /  $295 +1 FREE 8GB USB
Immunohistochemistry (IHC)
Product Name

DNAJB11, Polyclonal Antibody

Popular Item
Also Known As

Anti-DNAJB11 Antibody

Product Synonym Names
EDJ; ERJ3; HDJ9; DnaJ homolog subfamily B member 11; APOBEC1-binding protein 2; ABBP-2; DnaJ protein homolog 9; ER-associated DNAJ; ER-associated Hsp40 co-chaperone; Endoplasmic reticulum DNA J domain-containing protein 3; ER-resident protein ERdj3; ERdj3; ERj3p; HEDJ; Human DnaJ protein 9; hDj-9; PWP1-interacting protein 4
Antibody/Peptide Pairs
DNAJB11 peptide (MBS822726) is used for blocking the activity of DNAJB11 antibody (MBS821509)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence Length
358
OMIM
611341
3D Structure
ModBase 3D Structure for Q9UBS4
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Specificity
Recognizes endogenous levels of DNAJB11 protein.
Purity/Purification
The antibody was purified by immunogen affinity chromatography.
Form/Format
Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Immunogen
KLH-conjugated synthetic peptide encompassing a sequence within the center region of human DNAJB11. The exact sequence is proprietary.
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C for one year. Avoid freeze/thaw cycles.
Other Notes
Small volumes of anti-DNAJB11 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-DNAJB11 antibody
Rabbit polyclonal antibody to DNAJB11
Applications Tested/Suitable for anti-DNAJB11 antibody
Western Blot (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP)
Application Notes for anti-DNAJB11 antibody
WB (1/500 - 1/1000), IH (1/100 - 1/200), IP (1/10 - 1/100)

Western Blot (WB) of anti-DNAJB11 antibody
anti-DNAJB11 antibody Western Blot (WB) (WB) image
Immunohistochemistry (IHC) of anti-DNAJB11 antibody
Immunohistochemical analysis of DNAJB11 staining in human lung cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX.
anti-DNAJB11 antibody Immunohistochemistry (IHC) (IHC) image
NCBI/Uniprot data below describe general gene information for DNAJB11. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
40,514 Da
NCBI Official Full Name
dnaJ homolog subfamily B member 11
NCBI Official Synonym Full Names
DnaJ (Hsp40) homolog, subfamily B, member 11
NCBI Official Symbol
DNAJB11  [Similar Products]
NCBI Official Synonym Symbols
DJ9; EDJ; Dj-9; ERj3; ABBP2; ERdj3; ERj3p; ABBP-2; UNQ537; PRO1080
  [Similar Products]
NCBI Protein Information
dnaJ homolog subfamily B member 11; DnaJ protein 9; APOBEC1-binding protein 2; ER-resident protein ERdj3; PWP1-interacting protein 4; ER-associated DNAJ protein 3; ER-associated Hsp40 co-chaperone; endoplasmic reticulum DNA J domain-containing protein 3
UniProt Protein Name
DnaJ homolog subfamily B member 11
UniProt Synonym Protein Names
APOBEC1-binding protein 2; ABBP-2; DnaJ protein homolog 9; ER-associated DNAJ; ER-associated Hsp40 co-chaperone; Endoplasmic reticulum DNA J domain-containing protein 3; ER-resident protein ERdj3; ERdj3; ERj3p; HEDJ; Human DnaJ protein 9; hDj-9; PWP1-interacting protein 4
Protein Family
UniProt Gene Name
DNAJB11  [Similar Products]
UniProt Synonym Gene Names
EDJ; ERJ3; HDJ9; ABBP-2; ER-resident protein ERdj3; ERdj3; ERj3p; hDj-9  [Similar Products]
UniProt Entry Name
DJB11_HUMAN
NCBI Summary for DNAJB11
This gene encodes a soluble glycoprotein of the endoplasmic reticulum (ER) lumen that functions as a co-chaperone of binding immunoglobulin protein, a 70 kilodalton heat shock protein chaperone required for the proper folding and assembly of proteins in the ER. The encoded protein contains a highly conserved J domain of about 70 amino acids with a characteristic His-Pro-Asp (HPD) motif and may regulate the activity of binding immunoglobulin protein by stimulating ATPase activity. [provided by RefSeq, Mar 2014]
UniProt Comments for DNAJB11
DNAJB11: Serves as a co-chaperone for HSPA5. Binds directly to both unfolded proteins that are substrates for ERAD and nascent unfolded peptide chains, but dissociates from the HSPA5-unfolded protein complex before folding is completed. May help recruiting HSPA5 and other chaperones to the substrate. Stimulates HSPA5 ATPase activity.

Protein type: Secreted, signal peptide; Chaperone; Endoplasmic reticulum; RNA processing; Secreted

Chromosomal Location of Human Ortholog: 3q27.3

Cellular Component: membrane; endoplasmic reticulum lumen; endoplasmic reticulum; nucleus

Molecular Function: protein binding; unfolded protein binding

Biological Process: cellular protein metabolic process; unfolded protein response, activation of signaling protein activity; protein folding; unfolded protein response; mRNA modification
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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