O14576.2
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
Cytoplasmic dynein 1 intermediate chain 1
NCBI Official Synonym Full Names
dynein, cytoplasmic 1, intermediate chain 1
NCBI Protein Information
cytoplasmic dynein 1 intermediate chain 1; DH IC-1; dynein intermediate chain 1, cytosolic; cytoplasmic dynein intermediate chain 1; dynein, cytoplasmic, intermediate polypeptide 1
UniProt Protein Name
Cytoplasmic dynein 1 intermediate chain 1
UniProt Synonym Protein Names
Cytoplasmic dynein intermediate chain 1; Dynein intermediate chain 1, cytosolic; DH IC-1
UniProt Synonym Gene Names
UniProt Entry Name
DC1I1_HUMAN
UniProt Comments for DYNC1I1
DYNC1I1: Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. The intermediate chains mediate the binding of dynein to dynactin via its 150 kDa component (p150- glued) DCNT1. May play a role in mediating the interaction of cytoplasmic dynein with membranous organelles and kinetochores. Belongs to the dynein intermediate chain family. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Microtubule-binding; Motor; Motility/polarity/chemotaxis
Chromosomal Location of Human Ortholog: 7q21.3
Cellular Component: kinetochore; spindle pole; microtubule; recycling endosome; cytoplasmic dynein complex; perinuclear region of cytoplasm; cytosol; vesicle
Molecular Function: protein binding; spectrin binding; microtubule binding; motor activity; microtubule motor activity
Biological Process: metabolic process; vesicle transport along microtubule; antigen processing and presentation of exogenous peptide antigen via MHC class II
Research Articles on DYNC1I1
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Products associated with anti-DYNC1I1 antibody
Pathways associated with anti-DYNC1I1 antibody
Diseases associated with anti-DYNC1I1 antibody
Organs/Tissues associated with anti-DYNC1I1 antibody
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