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anti-EIF4E antibody :: Rabbit eukaryotic translation initiation factor 4E Polyclonal Antibody

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Catalog # MBS712008
Unit / Price
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  0.05 mL  /  $230 +1 FREE 8GB USB
  0.15 mL  /  $500 +1 FREE 8GB USB
anti-EIF4E antibody
Product Name

eukaryotic translation initiation factor 4E (EIF4E), Polyclonal Antibody

Full Product Name

Rabbit anti-human eukaryotic translation initiation factor 4E polyclonal Antibody

Product Synonym Names
eukaryotic translation initiation factor 4E; EIF4E; CBP; EIF4E1; EIF4EL1; EIF4F; MGC111573
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
OMIM
gene 615091
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Purity/Purification
Antigen Affinity Purified
Immunogen
Human CBP,EIF4E
Storage Buffer
PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20 degree C, Avoid freeze / thaw cycles.
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-6968 / sc-6967 / sc-13963
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of anti-EIF4E antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for anti-EIF4E antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
NCBI/Uniprot data below describe general gene information for EIF4E. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
27,260 Da[Similar Products]
NCBI Official Full Name
Eukaryotic translation initiation factor 4E
NCBI Official Synonym Full Names
eukaryotic translation initiation factor 4E
NCBI Official Symbol
EIF4E  [Similar Products]
NCBI Official Synonym Symbols
CBP; EIF4F; AUTS19; EIF4E1; EIF4EL1
  [Similar Products]
NCBI Protein Information
eukaryotic translation initiation factor 4E; eIF-4E; eIF-4F 25 kDa subunit; mRNA cap-binding protein; eukaryotic translation initiation factor 4E-like 1
UniProt Protein Name
Eukaryotic translation initiation factor 4E
UniProt Synonym Protein Names
eIF-4F 25 kDa subunit; mRNA cap-binding protein
UniProt Gene Name
EIF4E  [Similar Products]
UniProt Synonym Gene Names
EIF4EL1; EIF4F; eIF-4E; eIF4E  [Similar Products]
UniProt Entry Name
IF4E_HUMAN
NCBI Summary for EIF4E
The protein encoded by this gene is a component of the eukaryotic translation initiation factor 4F complex, which recognizes the 7-methylguanosine cap structure at the 5' end of cellular mRNAs. The encoded protein aids in translation initiation by recruiting ribosomes to the mRNA. Association of this protein with the 4F complex is the rate-limiting step in translation initiation. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012]
UniProt Comments for EIF4E
EIF4E: a protein of the eukaryotic initiation factor 4E family. Recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation of protein synthesis and facilitates ribosome binding by inducing the unwinding of the mRNAs secondary structures. Phosphorylation increases the ability of the protein to bind to mRNA caps and to form the EIF4F complex.

Protein type: Translation; Translation initiation

Chromosomal Location of Human Ortholog: 4q23

Cellular Component: mRNA cap complex; stress granule; cytoplasm; eukaryotic translation initiation factor 4F complex; cytosol

Molecular Function: protein binding; eukaryotic initiation factor 4G binding; translation initiation factor activity; RNA cap binding

Biological Process: regulation of translation; poly(A) tail shortening; mRNA export from nucleus; cellular protein metabolic process; translation; viral reproduction; cytokine and chemokine mediated signaling pathway; translational initiation; insulin receptor signaling pathway; gene expression; positive regulation of mitotic cell cycle; G1/S transition of mitotic cell cycle; lung development; mRNA catabolic process, deadenylation-dependent decay

Disease: Autism, Susceptibility To, 19
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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