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anti-EZR antibody :: Rabbit EZR Polyclonal Antibody

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Catalog # MBS2527345
Unit / Price
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  0.02 mL  /  $110 +1 FREE 8GB USB
  0.06 mL  /  $150 +1 FREE 8GB USB
  0.12 mL  /  $225 +1 FREE 8GB USB
  0.2 mL  /  $360 +1 FREE 8GB USB
Product Name

EZR, Polyclonal Antibody

Popular Item
Full Product Name

EZR Polyclonal Antibody

Product Synonym Names
CVL; CVIL; VIL2; HEL-S-105
Product Gene Name
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
OMIM
123900
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Purity/Purification
Antigen affinity purification
Concentration
1.2mg/mL (lot specific)
Immunogen
Recombinant protein of human EZR
Calculated Molecular Weight: 69kDa
Buffer
PBS with 0.05% sodium azide, 50% glycerol, pH7.3
Preparation and Storage
Store at -20 degree C (regular) and -80 degree C (long term). Avoid freeze / thaw cycles.
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of anti-EZR antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-EZR antibody
The cytoplasmic peripheral membrane protein encoded by this gene functions as a protein-tyrosine kinase substrate in microvilli. As a member of the ERM protein family, this protein serves as an intermediate between the plasma membrane and the actin cytoskeleton. This protein plays a key role in cell surface structure adhesion, migration and organization, and it has been implicated in various human cancers. A pseudogene located on chromosome 3 has been identified for this gene. Alternatively spliced variants have also been described for this gene.
Product Categories/Family for anti-EZR antibody
Applications Tested/Suitable for anti-EZR antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-EZR antibody
WB: 1:500-1:2000
IHC: 1:50-1:200

Western Blot (WB) of anti-EZR antibody
Western Blot analysis of Mouse kidney tissue using EZR Polyclonal Antibody at dilution of 1:300
anti-EZR antibody Western Blot (WB) (WB) image
Immunohistochemistry (IHC) of anti-EZR antibody
Immunohistochemistry of paraffin-embedded Human thyroid cancer using EZR Polyclonal Antibody at dilution of 1:30
anti-EZR antibody Immunohistochemistry (IHC) (IHC) image
Immunohistochemistry (IHC) of anti-EZR antibody
Immunohistochemistry of paraffin-embedded Human esophagus cancer using EZR Polyclonal Antibody at dilution of 1:30
anti-EZR antibody Immunohistochemistry (IHC) (IHC) image
NCBI/Uniprot data below describe general gene information for EZR. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
69,413 Da
NCBI Official Full Name
Ezrin
NCBI Official Synonym Full Names
ezrin
NCBI Official Symbol
NCBI Official Synonym Symbols
CVL; CVIL; VIL2; HEL-S-105
  [Similar Products]
NCBI Protein Information
ezrin; cytovillin 2; epididymis secretory protein Li 105; p81; villin 2 (ezrin); villin-2
UniProt Protein Name
Ezrin
UniProt Synonym Protein Names
Cytovillin; Villin-2; p81
Protein Family
UniProt Gene Name
UniProt Synonym Gene Names
UniProt Entry Name
EZRI_HUMAN
NCBI Summary for EZR
The cytoplasmic peripheral membrane protein encoded by this gene functions as a protein-tyrosine kinase substrate in microvilli. As a member of the ERM protein family, this protein serves as an intermediate between the plasma membrane and the actin cytoskeleton. This protein plays a key role in cell surface structure adhesion, migration and organization, and it has been implicated in various human cancers. A pseudogene located on chromosome 3 has been identified for this gene. Alternatively spliced variants have also been described for this gene. [provided by RefSeq, Jul 2008]
UniProt Comments for EZR
Ezrin: a member of the ERM family which includes radixin and moesin. ERM proteins appear to function as cross-linkers between plasma membranes and actin-based cytoskeletons. Plays a key role in cell surface structure adhesion, migration, and organization.

Protein type: Motility/polarity/chemotaxis; Cytoskeletal

Chromosomal Location of Human Ortholog: 6q25.3

Cellular Component: cortical cytoskeleton; extracellular space; focal adhesion; microvillus; basolateral plasma membrane; T-tubule; actin filament; cytosol; actin cytoskeleton; lipid raft; ruffle; extrinsic to membrane; membrane; apical part of cell; microvillus membrane; apical plasma membrane; nucleolus; plasma membrane; uropod; vesicle; filopodium

Molecular Function: actin filament binding; protein domain specific binding; protein binding; cell adhesion molecule binding

Biological Process: axon guidance; actin filament bundle formation; microvillus biogenesis; regulation of cell shape; leukocyte adhesion; filopodium formation; cytoskeletal anchoring; receptor internalization; membrane to membrane docking; establishment of epithelial cell polarity
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Products associated with anti-EZR antibody
 Reference Product  PubMed Publications
 PRKCA antibody  >1 publications with EZR and PRKCA
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