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anti-FBXO22 antibody :: Rabbit F-box protein 22 Polyclonal Antibody

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Catalog # MBS713986
Unit / Price
  0.05 mL  /  $230 +1 FREE 8GB USB
  0.15 mL  /  $500 +1 FREE 8GB USB
anti-FBXO22 antibody
Product Name

F-box protein 22 (FBXO22), Polyclonal Antibody

Also Known As

Rabbit anti-human F-box protein 22 polyclonal Antibody

Product Synonym Names
F-box protein 22; FBXO22; FBX22; FISTC1; FLJ13986; MGC31799
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence Length
403
OMIM
609096
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Purity/Purification
Antigen Affinity Purified
Immunogen
Human FBXO22
Storage Buffer
PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20 degree C, Avoid freeze / thaw cycles.
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-164371
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of anti-FBXO22 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for anti-FBXO22 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
NCBI/Uniprot data below describe general gene information for FBXO22. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
30,589 Da[Similar Products]
NCBI Official Full Name
F-box only protein 22 isoform a
NCBI Official Synonym Full Names
F-box protein 22
NCBI Official Symbol
FBXO22  [Similar Products]
NCBI Official Synonym Symbols
FBX22; FISTC1
  [Similar Products]
NCBI Protein Information
F-box only protein 22; F-box protein FBX22p44; FIST domain containing 1
UniProt Protein Name
F-box only protein 22
UniProt Synonym Protein Names
F-box protein FBX22p44
Protein Family
UniProt Gene Name
FBXO22  [Similar Products]
UniProt Synonym Gene Names
FBX22  [Similar Products]
UniProt Entry Name
FBX22_HUMAN
NCBI Summary for FBXO22
This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class and, as a transcriptional target of the tumor protein p53, is thought to be involved in degradation of specific proteins in response to p53 induction. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2010]
UniProt Comments for FBXO22
FBXO22: Substrate-recognition component of the SCF (SKP1-CUL1-F- box protein)-type E3 ubiquitin ligase complex. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Ubiquitin conjugating system; Ligase

Chromosomal Location of Human Ortholog: 15q24.2

Cellular Component: nucleus; Z disc

Molecular Function: ubiquitin-protein ligase activity

Biological Process: ubiquitin-dependent protein catabolic process; regulation of skeletal muscle fiber development; protein polyubiquitination; positive regulation of proteasomal ubiquitin-dependent protein catabolic process; protein modification process; nucleocytoplasmic transport; cellular response to starvation
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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