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anti-FBXO18 antibody :: Rabbit F-box protein, helicase, 18 Polyclonal Antibody

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Catalog # MBS713130
Unit / Price
  0.05 mL  /  $230 +1 FREE 8GB USB
  0.15 mL  /  $500 +1 FREE 8GB USB
anti-FBXO18 antibody
Product Name

F-box protein, helicase, 18 (FBXO18), Polyclonal Antibody

Also Known As

Rabbit anti-human F-box protein, helicase, 18 polyclonal Antibody

Product Synonym Names
F-box protein; helicase; 18; FBXO18; FBH1; FLJ14590; Fbx18; MGC131916; MGC141935; MGC141937
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence Length
986
OMIM
607222
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Purity/Purification
Antigen Affinity Purified
Immunogen
Human FBXO18
Storage Buffer
PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20 degree C, Avoid freeze / thaw cycles.
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of anti-FBXO18 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for anti-FBXO18 antibody
ELISA (EIA), Western Blot (WB)
NCBI/Uniprot data below describe general gene information for FBXO18. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
123,375 Da[Similar Products]
NCBI Official Full Name
F-box only protein 18 isoform 3
NCBI Official Synonym Full Names
F-box protein, helicase, 18
NCBI Official Symbol
FBXO18  [Similar Products]
NCBI Official Synonym Symbols
FBH1; Fbx18
  [Similar Products]
NCBI Protein Information
F-box only protein 18; F-box DNA helicase 1; F-box only protein, helicase, 18
UniProt Protein Name
F-box only protein 18
UniProt Synonym Protein Names
F-box DNA helicase 1
Protein Family
UniProt Gene Name
FBXO18  [Similar Products]
UniProt Synonym Gene Names
FBH1; FBX18  [Similar Products]
UniProt Entry Name
FBX18_HUMAN
NCBI Summary for FBXO18
This gene encodes a member of the F-box protein family, members of which are characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into three classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbx class. It contains an F-box motif and seven conserved helicase motifs, and has both DNA-dependent ATPase and DNA unwinding activities. Alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]
UniProt Comments for FBXO18
FBXO18: DNA-dependent ATPase. Unwinds double-stranded DNA in a 3' to 5' direction. Belongs to the helicase family. UvrD subfamily. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: EC 3.6.4.12; Helicase

Chromosomal Location of Human Ortholog: 10p15.1

Cellular Component: nucleus

Molecular Function: ATP-dependent DNA helicase activity; protein binding; DNA binding; ATP binding

Biological Process: positive regulation of protein amino acid phosphorylation; DNA catabolic process, endonucleolytic; DNA duplex unwinding
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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