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anti-FGF9 antibody :: Rabbit FGF9 Polyclonal Antibody

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Catalog # MBS175109
Unit / Price
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  0.1 mg  /  $315 +1 FREE 8GB USB
Product Name

FGF9, Polyclonal Antibody

Popular Item
Full Product Name

Polyclonal Anti-FGF9 antibody

Product Synonym Names
Fibroblast growth factor 9(FGF-9); fibroblast growth factor 9(glia-activating factor); FGF 9 antibody; FGF-9 antibody; FGF9 antibody; FGF9_HUMAN antibody; Fibroblast Growth Factor 9 antibody; GAF antibody; Glia Activating Factor antibody; Glia-activating factor antibody; HBFG 9 antibody; HBFG9 antibody; HBGF-9 antibody; Heparin-binding growth factor 9 antibody; MGC119914 antibody; MGC119915 antibody
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
OMIM
gene 612961
3D Structure
ModBase 3D Structure for P31371
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Reacts with: Human, Rat
Predicted to work with: Mouse
Specificity
No cross reactivity with other proteins
Purity/Purification
Immunogen affinity purified.
Form/Format
Lyophilized
Immunogen
A synthetic peptide corresponding to a sequence in the middle region of human FGF9 (150-164aa SNLYKHVDTGRRYYV), identical to the related mouse and rat sequences.
Contents
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
Reconstitution
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Preparation and Storage
At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen at -20 degree C for a longer time. Avoid repeated freezing and thawing.
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of anti-FGF9 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-FGF9 antibody
Description: Rabbit IgG polyclonal antibody for Fibroblast growth factor 9(FGF9) detection. Tested with WB, IHC-P in Human, Mouse, Rat.
Background: FGF 9, Fibroblast growth factor 9, is a protein that in humans is encoded by the FGF9 gene. The protein encoded by this gene is a member of the fibroblast growth factor(FGF) family. The FGF 9 gene contains 3 exons. By radioactive chromosomal in situ hybridization, the FGF 9 gene is mapped to chromosome 13q11-q12. This protein was isolated as a secreted factor that exhibits a growth-stimulating effect on cultured glial cells. In nervous system, this protein is produced mainly by neurons and may be important for glial cell development. Expression of the mouse homolog of this gene was found to be dependent on Sonic hedgehog(Shh) signaling.
Applications Tested/Suitable for anti-FGF9 antibody
Western Blot (WB), Immunohistochemistry (IHC) Paraffin
Application Notes for anti-FGF9 antibody
Western Blot
Concentration: 1.0-0.5ug/ml
Tested Species: Human, Rat
Predicted Species: Mouse

Immunohistochemistry (Paraffin-embedded Section)
Concentration: 0.5-1ug/ml
Tested Species: Rat
Predicted Species: Mouse
Antigen Retrieval: By Heat
Tested Species: In-house tested species with positive results

By Heat: Boiling the pafffin sections in 10mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Other applications have not been tested.
Optimal dilutions should be determined by end users.

Western Blot (WB) of anti-FGF9 antibody
Anti-FGF9 antibody, MBS175109, Western blotting
All lanes: Anti FGF9 (MBS175109) at 0.5ug/ml
Lane 1: Rat Brain Tissue Lysate at 50ug
Lane 2: HELA Whole Cell Lysate at 40ug
Predicted bind size: 23KD
Observed bind size: 23KD
anti-FGF9 antibody Western Blot (WB) (WB) image
Immunohistochemistry (IHC) of anti-FGF9 antibody
Anti-FGF9 antibody, MBS175109, IHC(P)
IHC(P): Rat Brain Tissue
anti-FGF9 antibody Immunohistochemistry (IHC) (IHC) image
NCBI/Uniprot data below describe general gene information for FGF9. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
23,441 Da
NCBI Official Full Name
Fibroblast growth factor 9
NCBI Official Synonym Full Names
fibroblast growth factor 9
NCBI Official Symbol
NCBI Official Synonym Symbols
GAF; FGF-9; SYNS3; HBFG-9; HBGF-9
  [Similar Products]
NCBI Protein Information
fibroblast growth factor 9; heparin-binding growth factor 9; fibroblast growth factor 9 (glia-activating factor)
UniProt Protein Name
Fibroblast growth factor 9
UniProt Synonym Protein Names
Glia-activating factor; GAF; Heparin-binding growth factor 9; HBGF-9
Protein Family
UniProt Gene Name
UniProt Synonym Gene Names
FGF-9; GAF; HBGF-9  [Similar Products]
UniProt Entry Name
FGF9_HUMAN
NCBI Summary for FGF9
The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein was isolated as a secreted factor that exhibits a growth-stimulating effect on cultured glial cells. In nervous system, this protein is produced mainly by neurons and may be important for glial cell development. Expression of the mouse homolog of this gene was found to be dependent on Sonic hedgehog (Shh) signaling. Mice lacking the homolog gene displayed a male-to-female sex reversal phenotype, which suggested a role in testicular embryogenesis. [provided by RefSeq, Jul 2008]
UniProt Comments for FGF9
FGF9: Plays an important role in the regulation of embryonic development, cell proliferation, cell differentiation and cell migration. May have a role in glial cell growth and differentiation during development, gliosis during repair and regeneration of brain tissue after damage, differentiation and survival of neuronal cells, and growth stimulation of glial tumors. Defects in FGF9 are the cause of multiple synostoses syndrome type 3 (SYNS3). Multiple synostoses syndrome is an autosomal dominant condition characterized by progressive joint fusions of the fingers, wrists, ankles and cervical spine, characteristic facies and progressive conductive deafness. Belongs to the heparin-binding growth factors family.

Protein type: Cytokine

Chromosomal Location of Human Ortholog: 13q11-q12

Cellular Component: extracellular space; cytoplasm; extracellular region; basement membrane

Molecular Function: heparin binding; growth factor activity; fibroblast growth factor receptor binding

Biological Process: negative regulation of Wnt receptor signaling pathway; nerve growth factor receptor signaling pathway; embryonic skeletal development; negative regulation of transcription from RNA polymerase II promoter; signal transduction; positive regulation of vascular endothelial growth factor receptor signaling pathway; positive regulation of activin receptor signaling pathway; substantia nigra development; cell-cell signaling; positive regulation of MAPKKK cascade; protein import into nucleus; male sex determination; positive regulation of mesenchymal cell proliferation; positive regulation of cell proliferation; positive regulation of smoothened signaling pathway; chondrocyte differentiation; angiogenesis; regulation of timing of cell differentiation; embryonic gut development; positive regulation of cardiac muscle cell proliferation; embryonic limb morphogenesis; epidermal growth factor receptor signaling pathway; inner ear morphogenesis; fibroblast growth factor receptor signaling pathway; phosphoinositide-mediated signaling; male gonad development; osteoblast differentiation; positive regulation of cell division; insulin receptor signaling pathway; innate immune response; positive regulation of epithelial cell proliferation

Disease: Multiple Synostoses Syndrome 3
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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