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anti-FRS2 antibody :: Rabbit fibroblast growth factor receptor substrate 2 Polyclonal Antibody

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Catalog # MBS710247
Unit / Price
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  0.05 mL  /  $230 +1 FREE 8GB USB
  0.15 mL  /  $500 +1 FREE 8GB USB
anti-FRS2 antibody
Product Name

fibroblast growth factor receptor substrate 2 (FRS2), Polyclonal Antibody

Full Product Name

Rabbit anti-human fibroblast growth factor receptor substrate 2 polyclonal Antibody

Product Synonym Names
fibroblast growth factor receptor substrate 2; FRS2; FRS2A; FRS2alpha; SNT; SNT-1; SNT1
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
OMIM
607743
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Purity/Purification
Antigen Affinity Purified
Immunogen
Human FRS2
Storage Buffer
PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20 degree C, Avoid freeze / thaw cycles.
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-51489 / sc-51490 / sc-51489 / sc-51490 / sc-51491 / sc-8318
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of anti-FRS2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for anti-FRS2 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
NCBI/Uniprot data below describe general gene information for FRS2. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
57,029 Da[Similar Products]
NCBI Official Full Name
fibroblast growth factor receptor substrate 2
NCBI Official Synonym Full Names
fibroblast growth factor receptor substrate 2
NCBI Official Symbol
NCBI Official Synonym Symbols
SNT; SNT1; FRS2A; SNT-1; FRS2alpha
  [Similar Products]
NCBI Protein Information
fibroblast growth factor receptor substrate 2; FGFR substrate 2; FGFR signalling adaptor; FGFR-signaling adaptor SNT; suc1-associated neurotrophic factor target 1
UniProt Protein Name
Fibroblast growth factor receptor substrate 2
UniProt Synonym Protein Names
FGFR-signaling adaptor SNT; Suc1-associated neurotrophic factor target 1; SNT-1
UniProt Gene Name
UniProt Synonym Gene Names
FGFR substrate 2; SNT-1  [Similar Products]
UniProt Entry Name
FRS2_HUMAN
UniProt Comments for FRS2
FRS2: an adaptor protein involved in fibroblast growth factor receptor (FGFR) signaling. Plays an important role in linking FGFR and nerve growth factor receptors with Ras/MAPK signaling pathways.

Protein type: Adaptor/scaffold

Chromosomal Location of Human Ortholog: 12q15

Cellular Component: membrane; integral to plasma membrane; plasma membrane; intercellular junction; endosome

Molecular Function: protein binding; neurotrophin TRKA receptor binding; phosphatase activator activity; transmembrane receptor protein tyrosine kinase adaptor protein activity; insulin receptor binding; fibroblast growth factor receptor binding

Biological Process: epidermal growth factor receptor signaling pathway; fibroblast growth factor receptor signaling pathway; phosphoinositide-mediated signaling; nerve growth factor receptor signaling pathway; activation of MAPKK activity; activation of MAPK activity; gastrulation with mouth forming second; regulation of epithelial cell proliferation; regulation of apoptosis; G-protein coupled receptor protein signaling pathway; determination of anterior/posterior axis, embryo; induction of an organ; neuroblast proliferation; forebrain development; insulin receptor signaling pathway; innate immune response; optic placode formation involved in camera-type eye; transmembrane receptor protein tyrosine phosphatase signaling pathway
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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