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anti-FMO2 antibody :: Rabbit flavin containing monooxygenase 2 (non-functional) Polyclonal Antibody

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Catalog # MBS711166
Unit / Price
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  0.05 mL  /  $230 +1 FREE 8GB USB
  0.15 mL  /  $500 +1 FREE 8GB USB
anti-FMO2 antibody
Product Name

flavin containing monooxygenase 2 (non-functional) (FMO2), Polyclonal Antibody

Full Product Name

Rabbit anti-human flavin containing monooxygenase 2 (non-functional) polyclonal Antibody

Product Synonym Names
flavin containing monooxygenase 2 (non-functional); FMO2; FLJ40826; FMO1B1
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
OMIM
603955
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Purity/Purification
Antigen Affinity Purified
Immunogen
Human FMO2
Storage Buffer
PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20 degree C, Avoid freeze / thaw cycles.
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-83827
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of anti-FMO2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for anti-FMO2 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
NCBI/Uniprot data below describe general gene information for FMO2. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
53,644 Da[Similar Products]
NCBI Official Full Name
Flavin containing monooxygenase 2 (non-functional)
NCBI Official Synonym Full Names
flavin containing monooxygenase 2 (non-functional)
NCBI Official Symbol
NCBI Official Synonym Symbols
FMO1B1
  [Similar Products]
NCBI Protein Information
dimethylaniline monooxygenase [N-oxide-forming] 2; dimethylaniline monooxygenase [N-oxide-forming] 2; FMO, pulmonary; dimethylaniline oxidase 2; pulmonary flavin-containing monooxygenase 2
UniProt Protein Name
Dimethylaniline monooxygenase [N-oxide-forming] 2
UniProt Synonym Protein Names
Dimethylaniline oxidase 2; FMO 1B1; Pulmonary flavin-containing monooxygenase 2; FMO 2
UniProt Gene Name
UniProt Synonym Gene Names
FMO 2  [Similar Products]
UniProt Entry Name
FMO2_HUMAN
NCBI Summary for FMO2
This gene encodes a flavin-containing monooxygenase family member. It is an NADPH-dependent enzyme that catalyzes the N-oxidation of some primary alkylamines through an N-hydroxylamine intermediate. However, some human populations contain an allele (FMO2*2A) with a premature stop codon, resulting in a protein that is C-terminally-truncated, has no catalytic activity, and is likely degraded rapidly. This gene is found in a cluster with other related family members on chromosome 1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2014]
UniProt Comments for FMO2
FMO2: Catalyzes the N-oxidation of certain primary alkylamines to their oximes via an N-hydroxylamine intermediate. Inactive toward certain tertiary amines, such as imipramine or chloropromazine. Can catalyze the S-oxidation of methimazole. The truncated form is catalytically inactive. Belongs to the FMO family.

Protein type: Xenobiotic Metabolism - drug metabolism - cytochrome P450; Oxidoreductase; EC 1.14.13.8

Chromosomal Location of Human Ortholog: 1q24.3

Cellular Component: endoplasmic reticulum membrane; membrane; integral to membrane

Molecular Function: FAD binding; NADP binding; flavin-containing monooxygenase activity; monooxygenase activity

Biological Process: organic acid metabolic process; toxin metabolic process; xenobiotic metabolic process; drug metabolic process; NADP metabolic process
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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