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anti-GADD45B antibody :: Rabbit GADD45B Polyclonal Antibody

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Catalog # MBS9603890
Unit / Price
  0.1 mL  /  $255 +1 FREE 8GB USB
  0.2 mL  /  $295 +1 FREE 8GB USB
Western Blot (WB)
Product Name

GADD45B, Polyclonal Antibody

Popular Item
Also Known As

GADD45B Antibody

Product Synonym Names
GA45B_HUMAN; GADD45 Beta; Gadd45b; GADD45BETA; Growth arrest and DNA damage inducible 45 beta; Growth arrest and DNA damage inducible beta; Growth arrest and DNA damage-inducible gene GADD45, beta; Growth arrest and DNA damage-inducible protein GADD45 beta; Growth arrest and DNA-damage-inducible protein GADD45 beta; MY118; MYD118; MYD118, mouse, homolog of; Myeloid differentiation primary response gene; Myeloid differentiation primary response protein MyD118; Negative growth regulatory protein MyD118; Negative growth-regulatory protein MyD118
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence Length
160
3D Structure
ModBase 3D Structure for O75293
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Specificity
GADD45B antibody detects endogenous levels of total GADD45B
Purity/Purification
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.
Form/Format
Liquid
Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1mg/ml (lot specific)
Immunogen
A synthesized peptide
Conjugation
Unconjugated
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Supply Chain Verification
Manufactured in a lab with traceable raw materials. Bulk orders can typically be prepared to the customer’s specifications, please inquire.
Other Notes
Small volumes of anti-GADD45B antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-GADD45B antibody
Description: Involved in the regulation of growth and apoptosis. Mediates activation of stress-responsive MTK1/MEKK4 MAPKKK.
Subunit Structure: Interacts with GADD45GIP1.
Similarity: Belongs to the GADD45 family.
Applications Tested/Suitable for anti-GADD45B antibody
Western Blot (WB), ELISA (EIA)
Application Notes for anti-GADD45B antibody
WB: 1:500-1:2000

Western Blot (WB) of anti-GADD45B antibody
Western blot analysis of GADD45B expression in Jurkat cell lysate; Fetal liver cell lysate; Fetal heart cell lysate; A549 cell lysate, The lane on the left is treated with the antigen-specific peptide.
anti-GADD45B antibody Western Blot (WB) (WB) image
NCBI/Uniprot data below describe general gene information for GADD45B. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
Observed: 18 kDa
Predicted: 18 kDa
NCBI Official Full Name
growth arrest and DNA damage-inducible protein GADD45 beta
NCBI Official Synonym Full Names
growth arrest and DNA damage inducible beta
NCBI Official Symbol
GADD45B  [Similar Products]
NCBI Official Synonym Symbols
MYD118; GADD45BETA
  [Similar Products]
NCBI Protein Information
growth arrest and DNA damage-inducible protein GADD45 beta
UniProt Protein Name
Growth arrest and DNA damage-inducible protein GADD45 beta
UniProt Synonym Protein Names
Myeloid differentiation primary response protein MyD118; Negative growth regulatory protein MyD118
UniProt Gene Name
GADD45B  [Similar Products]
UniProt Synonym Gene Names
MYD118  [Similar Products]
NCBI Summary for GADD45B
This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The genes in this group respond to environmental stresses by mediating activation of the p38/JNK pathway. This activation is mediated via their proteins binding and activating MTK1/MEKK4 kinase, which is an upstream activator of both p38 and JNK MAPKs. The function of these genes or their protein products is involved in the regulation of growth and apoptosis. These genes are regulated by different mechanisms, but they are often coordinately expressed and can function cooperatively in inhibiting cell growth. [provided by RefSeq, Jul 2008]
UniProt Comments for GADD45B
Involved in the regulation of growth and apoptosis. Mediates activation of stress-responsive MTK1/MEKK4 MAPKKK.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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