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anti-GALNT10 antibody :: Rabbit GALNT10 Polyclonal Antibody

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Catalog # MBS150336
Unit / Price
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  0.1 mg  /  $375 +1 FREE 8GB USB
Product Name

GALNT10, Polyclonal Antibody

Popular Item
Full Product Name

GALNT10 Antibody

Product Synonym Names
GALNT10; GALNACT10; PPGALNACT10; PPGANTASE10; Polypeptide N-acetylgalactosaminyltransferase 10; Polypeptide GalNAc transferase 10; GalNAc-T10; UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 10 (GalNAc-T10)
Antibody/Peptide Pairs
GALNT10 peptide (MBS152901) is used for blocking the activity of GALNT10 antibody (MBS150336)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
OMIM
608043
3D Structure
ModBase 3D Structure for Q86SR1
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Purity/Purification
GALNT10 Antibody is affinity chromatography purified via peptide column.
Form/Format
Liquid
Concentration
1 mg/mL (lot specific)
Conjugate
Unconjugated
Immunogen
GALNT10 antibody was raised against an 18 amino acid synthetic peptide near the carboxy terminus of human GALNT10.
Buffer
GALNT10 Antibody is supplied in PBS containing 0.02% sodium azide.
Preparation and Storage
GALNT10 antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Other Notes
Small volumes of anti-GALNT10 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-GALNT10 antibody
GALNT10 Antibody: Protein glycosylation is an important biological process that is carried out by a large family of glycosyltransferases that catalyze the synthesis of oligosaccharides and glycoconjugates. Polypeptide GalNAc transferases initiate the synthesis of mucin-type oligosaccharides by transferring GalNAc from UDP-GalNAc to the hydroxyl group of either a serine or threonine residue on the polypeptide acceptor. Polypeptide galactoaminyltransferase 10 (GALNT10) belongs to the polypeptide N-acetylgalactosaminyl-transferase (pp-GalNAc-T) protein family. Following expression in insect cells, recombinant GALNT10 showed significant GalNAcT activity toward mucin-derived peptides, and it utilized both non-glycosylated and glycosylated peptide substrates. GALNT10 mRNA is highly expressed in several distinct hypothalamic, thalamic, and amygdaloid nuclei in mouse brain. At least four isoforms of GALNT10 are known to exist.
Applications Tested/Suitable for anti-GALNT10 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
Application Notes for anti-GALNT10 antibody
GALNT10 antibody can be used for detection of GALNT10 by Western blot at 1 - 2 mug/mL. Antibody can also be used for immunohistochemistry starting at 2.5 mug/mL. For immunofluorescence start at 20 mug/mL.

Western Blot (WB) of anti-GALNT10 antibody
Western blot analysis of GALNT10 in SK-N-SH cell lysate with GALNT10 antibody at (A) 1 and (B) 2 μg/mL.
anti-GALNT10 antibody Western Blot (WB) (WB) image
Immunohistochemistry (IHC) of anti-GALNT10 antibody
Immunohistochemistry of GALNT10 in human brain tissue with GALNT10 antibody at 2.5 μg/mL.
anti-GALNT10 antibody Immunohistochemistry (IHC) (IHC) image
Immunofluorescence (IF) of anti-GALNT10 antibody
Immunofluorescence of GALNT10 in Human Brain cells with GALNT10 antibody at 20 μg/mL.
anti-GALNT10 antibody Immunofluorescence (IF) image
NCBI/Uniprot data below describe general gene information for GALNT10. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
31,833 Da
NCBI Official Full Name
polypeptide N-acetylgalactosaminyltransferase 10
NCBI Official Synonym Full Names
polypeptide N-acetylgalactosaminyltransferase 10
NCBI Official Symbol
GALNT10  [Similar Products]
NCBI Official Synonym Symbols
GALNACT10; PPGALNACT10; PPGANTASE10
  [Similar Products]
NCBI Protein Information
polypeptide N-acetylgalactosaminyltransferase 10; GalNAc transferase 10; UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 10; UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 10 (GalNAc-T10)
UniProt Protein Name
Polypeptide N-acetylgalactosaminyltransferase 10
UniProt Synonym Protein Names
Polypeptide GalNAc transferase 10; GalNAc-T10; pp-GaNTase 10; Protein-UDP acetylgalactosaminyltransferase 10; UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 10
UniProt Gene Name
GALNT10  [Similar Products]
UniProt Synonym Gene Names
GalNAc-T10; pp-GaNTase 10  [Similar Products]
UniProt Entry Name
GLT10_HUMAN
NCBI Summary for GALNT10
This gene encodes a member of the GalNAc polypeptide N-acetylgalactosaminyltransferases. These enzymes catalyze the first step in the synthesis of mucin-type oligosaccharides. These proteins transfer GalNAc from UDP-GalNAc to either serine or threonine residues of polypeptide acceptors. The protein encoded by this locus may have increased catalytic activity toward glycosylated peptides compared to activity toward non-glycosylated peptides.[provided by RefSeq, Apr 2010]
UniProt Comments for GALNT10
GALNT10: Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D- galactosamine residue to a serine or threonine residue on the protein receptor. Has activity toward Muc5Ac and EA2 peptide substrates. Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily. 4 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Transferase; Glycan Metabolism - O-glycan biosynthesis; EC 2.4.1.41

Chromosomal Location of Human Ortholog: 5q33.2

Cellular Component: Golgi membrane; integral to membrane

Molecular Function: metal ion binding; polypeptide N-acetylgalactosaminyltransferase activity; carbohydrate binding

Biological Process: protein amino acid O-linked glycosylation; cellular protein metabolic process; O-glycan processing; post-translational protein modification
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Organs/Tissues associated with anti-GALNT10 antibody
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