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anti-GFAP antibody :: Rabbit Glial fibrillary acidic protein Polyclonal Antibody

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Catalog # MBS1489669
Unit / Price
  0.05 mg  /  $160 +1 FREE 8GB USB
  0.1 mg  /  $235 +1 FREE 8GB USB
Product Name

Glial fibrillary acidic protein (GFAP), Polyclonal Antibody

Popular Item
Also Known As

Rabbit anti-human Glial fibrillary acidic protein polyclonal Antibody

Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence Length
431
OMIM
137780
3D Structure
ModBase 3D Structure for P14136
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat. Other species are not tested. Please decide the specificity
Purity/Purification
Caprylic Acid Ammonium Sulfate Precipitation Purified
Storage Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Conjugate
Non-conjugated
Immunogen
Recombinant human Glial fibrillary acidic protein
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-6170 / sc-6171 / sc-9065
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of anti-GFAP antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-GFAP antibody
GFAP, a class-III intermediate filament, is a cell-specific marker that, during the development of the central nervous system, distinguishes astrocytes from other glial cells.
Applications Tested/Suitable for anti-GFAP antibody
ELISA (EIA), Western Blot (WB)

Western Blot (WB) of anti-GFAP antibody
Western Blot
Positive WB detected in:Mouse heart tissue,Mouse kidney tissue,Mouse brain tissue
All lanes: Gfap antibody at 3ug/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 50,51 kDa
Observed band size: 50 kDa

anti-GFAP antibody Western Blot (WB) (WB) image
Western Blot (WB) of anti-GFAP antibody
Western Blot
Positive WB detected in: MCF-7 whole cell lysate
All lanes: GFAP antibody at 3ug/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 50,51 KDa
Observed band size: 50,51 KDa

anti-GFAP antibody Western Blot (WB) (WB) image
Immunohistochemistry (IHC) of anti-GFAP antibody
Immunohistochemistry analysis of human brain tissue using MBS1489669 at dilution of 1:100
anti-GFAP antibody Immunohistochemistry (IHC) (IHC) image
Immunohistochemistry (IHC) of anti-GFAP antibody
Immunohistochemistry analysis of human glioma cancer using MBS1489669 at dilution of 1:100
anti-GFAP antibody Immunohistochemistry (IHC) (IHC) image
Immunofluorescence (IF) of anti-GFAP antibody
Immunofluorescent analysis of A549 cells using MBS1489669 at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
anti-GFAP antibody Immunofluorescence (IF) image
NCBI/Uniprot data below describe general gene information for GFAP. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
49,508 Da
NCBI Official Full Name
glial fibrillary acidic protein isoform 2
NCBI Official Synonym Full Names
glial fibrillary acidic protein
NCBI Official Symbol
NCBI Official Synonym Symbols
ALXDRD
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NCBI Protein Information
glial fibrillary acidic protein
UniProt Protein Name
Glial fibrillary acidic protein
UniProt Gene Name
UniProt Synonym Gene Names
UniProt Entry Name
GFAP_HUMAN
NCBI Summary for GFAP
This gene encodes one of the major intermediate filament proteins of mature astrocytes. It is used as a marker to distinguish astrocytes from other glial cells during development. Mutations in this gene cause Alexander disease, a rare disorder of astrocytes in the central nervous system. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Oct 2008]
UniProt Comments for GFAP
GFAP: a class-III intermediate filament protein. A cell-specific marker that, during the development of the central nervous system, distinguishes astrocytes from other glial cells. Mutations in this gene cause Alexander disease, a rare disorder of astrocytes in the central nervous system. An additional transcript variant isoform has been described, but its full length sequence has not been determined.

Protein type: Cytoskeletal

Chromosomal Location of Human Ortholog: 17q21

Cellular Component: cytoplasm; cytosol; intermediate filament; intermediate filament cytoskeleton; lysosome; membrane; myelin sheath

Molecular Function: integrin binding; kinase binding; protein binding; structural constituent of cytoskeleton

Biological Process: astrocyte development; Bergmann glial cell differentiation; extracellular matrix organization and biogenesis; intermediate filament organization; neurite regeneration; regulation of neurotransmitter uptake; regulation of protein complex assembly; response to wounding

Disease: Alexander Disease
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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