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anti-GluR5 antibody :: Rabbit GluR5 Polyclonal Antibody

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Catalog # MBS9504612
Unit / Price
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  0.05 mg  /  $245 +1 FREE 8GB USB
  0.1 mg  /  $335 +1 FREE 8GB USB
Product Name

GluR5, Polyclonal Antibody

Full Product Name

GluR5 Antibody

Product Synonym Names
Glutamate receptor; ionotropic kainate 1; Glutamate receptor 5; GluR-5; GluR5; Excitatory amino acid receptor 3; EAA3; GRIK1
Product Synonym Gene Name
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
OMIM
L19058 mRNA
3D Structure
ModBase 3D Structure for P39086
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Specificity
GluR5 Antibody detects endogenous levels of total GluR5 protein.
Purity/Purification
Purified from rabbit antiserum by affinity-chromatography using immunogen.
Form/Format
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1 mg/ml (lot specific)
Target Modification
Unmodified/Total
Immunogen
The antiserum was produced against synthesized peptide derived from human GluR5.
Immunogen Range
Oct-59
Preparation and Storage
Stable at -20 degree C for at least 1 year.
Other Notes
Small volumes of anti-GluR5 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for anti-GluR5 antibody
Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA)
Application Notes for anti-GluR5 antibody
WB: 1:500~1:1000
IHC: 1:50~1:100
ELISA: 1:5000

Immunohistochemistry (IHC) of anti-GluR5 antibody
Immunohistochemistry analysis of paraffin-embedded human brain tissue, using GluR5 Antibody. The picture on the right is blocked with the synthesized peptide.
anti-GluR5 antibody Immunohistochemistry (IHC) (IHC) image
Western Blot (WB) of anti-GluR5 antibody
Western blot analysis of lysates from mouse brain, using GluR5 Antibody. The lane on the right is blocked with the synthesized peptide.
anti-GluR5 antibody Western Blot (WB) (WB) image
NCBI/Uniprot data below describe general gene information for GluR5. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
103 kDa
NCBI Official Full Name
glutamate receptor ionotropic, kainate 1 isoform 1
NCBI Official Synonym Full Names
glutamate ionotropic receptor kainate type subunit 1
NCBI Official Symbol
GRIK1  [Similar Products]
NCBI Official Synonym Symbols
EAA3; EEA3; GLR5; GLUR5; GluK1; gluR-5
  [Similar Products]
NCBI Protein Information
glutamate receptor ionotropic, kainate 1
UniProt Protein Name
Glutamate receptor ionotropic, kainate 1
UniProt Synonym Protein Names
Excitatory amino acid receptor 3; EAA3; Glutamate receptor 5; GluR-5; GluR5
UniProt Gene Name
GRIK1  [Similar Products]
UniProt Synonym Gene Names
GLUR5; GluK1; EAA3; GluR-5; GluR5  [Similar Products]
NCBI Summary for GluR5
Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to the kainate family of glutamate receptors, which are composed of four subunits and function as ligand-activated ion channels. The subunit encoded by this gene is subject to RNA editing (CAG->CGG; Q->R) within the second transmembrane domain, which is thought to alter the properties of ion flow. Alternative splicing, resulting in transcript variants encoding different isoforms, has been noted for this gene. [provided by RefSeq, Jul 2008]
UniProt Comments for GluR5
Ionotropic glutamate receptor. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist. May be involved in the transmission of light information from the retina to the hypothalamus.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Organs/Tissues associated with anti-GluR5 antibody
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